Phosphoramidic Acid

Phosphoramidic Acid

SCHEMBL2237983

CCN=C(N)N.CCN=C(N)N.NP(=O)(O)O

nearest known ligand 0.43

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Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
GGPS1 O95749 1/20 0.43
NOS1 P29475 1/20 0.39
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
GABBR2 O75899 1/20 0.34
GABBR1 Q9UBS5 1/20 0.34
HSD17B10 Q99714 1/20 0.34
LAP3 P28838 1/20 0.33
TPI1 P60174 1/20 0.33
METAP1 P53582 1/20 0.32
NPSR1 Q6W5P4 1/20 0.31
FDPS P14324 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL689417 0.83
Hydrochloric Acid SCHEMBL27430194 0.80
Hydrochloric Acid SCHEMBL6777486 0.80
SCHEMBL28850341 0.77 NOS1 (0.46) NOS1MEN1KMT2AHSD17B10NPSR1
Sulfuric Acid SCHEMBL6049591 0.76 BLM (0.50) NOS1MEN1KMT2AHSD17B10NPSR1
Guanidine SCHEMBL28317239 0.75 NOS1 (0.43) NOS1MEN1KMT2AHSD17B10
Phosphoramidic Acid SCHEMBL813235 0.70
Phosphoramidic Acid SCHEMBL27488487 0.69
Phosphoramidic Acid SCHEMBL408717 0.67 KDM4E (0.50) GABBR2GABBR1HSD17B10LAP3METAP1
Phosphoramidic Acid SCHEMBL25846 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2193204-B1 COMPOSITIONS COMPRISING LIPOPHOSPHORAMIDES AND THEIR USES IN GENE THERAPY UNIV BRETAGNE OCCIDENTALE (FR) 2011-08-31 EP disclosed