Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.73 |
| ▸ | LMNA | P02545 | 2/20 | 0.73 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | ALPL | P05186 | 1/20 | 0.43 |
| ▸ | ALPI | P09923 | 1/20 | 0.43 |
| ▸ | ALPG | P10696 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21159809 | 1.00 | GAA (0.73) | GAALMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL19924470 | 0.84 | LMNA (1.00) | GAALMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL21160014 | 0.84 | GAA (0.63) | GAALMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL21159808 | 0.82 | GAA (0.69) | GAALMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL21160366 | 0.82 | GAA (0.69) | GAALMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL21160004 | 0.82 | RAB9A (0.49) | GAALMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL21159814 | 0.68 | LMNA (0.56) | GAALMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL2152542 | 0.68 | KMT2A (0.66) | GAALMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL16545220 | 0.67 | EPHX2 (0.71) | GAALMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8233566 | 0.67 | EPHX2 (0.71) | GAALMNAMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10759749-B2 | Therapeutic agent for diabetes | JCR PHARMACEUTICALS CO., LTD. (JP) | 2020-09-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10759749-B2 | Therapeutic agent for diabetes | GPR119, IAPP, DPP4 | GAA 58/4885LMNA 4517/4885MEN1 3662/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.