Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 2/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.31 |
| ▸ | TRPC3 | Q13507 | 3/20 | 0.31 |
| ▸ | TRPC6 | Q9Y210 | 3/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.31 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.31 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19894028 | 0.81 | HCRTR1 (0.34) | CCKBRHCRTR1HCRTR2NR1I2ADRA2B | |
| SCHEMBL19894085 | 0.78 | HCRTR2 (0.50) | HCRTR1HCRTR2NR1I2ADRA2BKCNH2 | |
| SCHEMBL19893971 | 0.78 | HCRTR1 (0.44) | HCRTR1HCRTR2 | |
| SCHEMBL19894072 | 0.76 | HCRTR1 (0.37) | HCRTR1HCRTR2 | |
| SCHEMBL19894143 | 0.72 | HCRTR2 (0.44) | HCRTR1HCRTR2 | |
| SCHEMBL19893988 | 0.72 | SORD (0.33) | HCRTR1HCRTR2 | |
| SCHEMBL19894084 | 0.70 | HCRTR2 (0.57) | HCRTR1HCRTR2 | |
| SCHEMBL19893987 | 0.70 | HCRTR2 (0.57) | HCRTR1HCRTR2 | |
| SCHEMBL23018154 | 0.70 | HCRTR1 (0.66) | HCRTR1HCRTR2NR1I2ADRA2BKCNH2 | |
| SCHEMBL17515601 | 0.70 | HCRTR1 (0.66) | HCRTR1HCRTR2NR1I2ADRA2BKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3287454-B1 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICALS CO (JP) | 2020-09-02 | — | — | EP | disclosed |