Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.41 |
| ▸ | KIFC1 | Q9BW19 | 4/20 | 0.40 |
| ▸ | PLG | P00747 | 1/20 | 0.40 |
| ▸ | GCGR | P47871 | 3/20 | 0.39 |
| ▸ | ADCY6 | O43306 | 2/20 | 0.39 |
| ▸ | ADCY3 | O60266 | 2/20 | 0.39 |
| ▸ | ADCY9 | O60503 | 2/20 | 0.39 |
| ▸ | ADCY5 | O95622 | 2/20 | 0.39 |
| ▸ | ADCY8 | P40145 | 2/20 | 0.39 |
| ▸ | ADCY7 | P51828 | 2/20 | 0.39 |
| ▸ | ADCY2 | Q08462 | 2/20 | 0.39 |
| ▸ | ADCY1 | Q08828 | 2/20 | 0.39 |
| ▸ | ADCY4 | Q8NFM4 | 2/20 | 0.39 |
| ▸ | CTSS | P25774 | 5/20 | 0.38 |
| ▸ | CTSK | P43235 | 3/20 | 0.38 |
| ▸ | CTSB | P07858 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22384056 | 0.95 | L3MBTL1 (0.41) | L3MBTL1KLKB1KIFC1PLGGCGR | |
| SCHEMBL16305639 | 0.95 | L3MBTL1 (0.41) | L3MBTL1KLKB1KIFC1PLGGCGR | |
| SCHEMBL16305989 | 0.92 | GCGR (0.47) | L3MBTL1KLKB1KIFC1PLGGCGR | |
| SCHEMBL16305638 | 0.88 | L3MBTL1 (0.46) | L3MBTL1KIFC1PLGGCGRADCY6 | |
| SCHEMBL16305939 | 0.88 | GCGR (0.48) | L3MBTL1KLKB1KIFC1PLGGCGR | |
| SCHEMBL22384200 | 0.88 | CTSS (0.42) | L3MBTL1KLKB1KIFC1PLGGCGR | |
| SCHEMBL16375225 | 0.88 | CTSS (0.42) | L3MBTL1KLKB1KIFC1PLGGCGR | |
| SCHEMBL16294773 | 0.87 | GCGR (0.48) | L3MBTL1KLKB1PLGGCGRADCY6 | |
| SCHEMBL16294771 | 0.87 | GCGR (0.48) | L3MBTL1KLKB1PLGGCGRADCY6 | |
| SCHEMBL16305641 | 0.85 | L3MBTL1 (0.46) | L3MBTL1KLKB1KIFC1PLGGCGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3230276-B1 | GLP-1 RECEPTOR MODULATORS | CELGENE INT II SARL (CH) | 2020-09-02 | — | — | EP | disclosed |