Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 5/20 | 0.42 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.40 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.40 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.40 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.39 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.38 |
| ▸ | DDR2 | Q16832 | 2/20 | 0.38 |
| ▸ | CTSL | P07711 | 2/20 | 0.38 |
| ▸ | KIFC1 | Q9BW19 | 1/20 | 0.38 |
| ▸ | PLG | P00747 | 1/20 | 0.38 |
| ▸ | GCGR | P47871 | 2/20 | 0.37 |
| ▸ | ACE | P12821 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16375225 | 1.00 | CTSS (0.42) | CTSSPSMB1PSMB8PSMB9PSMB5 | |
| SCHEMBL16294799 | 0.92 | CTSS (0.45) | CTSSL3MBTL1KLKB1DDR1MAPK14 | |
| SCHEMBL16294798 | 0.92 | CTSS (0.45) | CTSSL3MBTL1KLKB1DDR1MAPK14 | |
| SCHEMBL22756160 | 0.90 | PSMB5 (0.39) | CTSSPSMB1PSMB8PSMB9PSMB5 | |
| SCHEMBL16306026 | 0.88 | CTSS (0.37) | CTSSPSMB1PSMB8PSMB9PSMB5 | |
| SCHEMBL22384055 | 0.88 | L3MBTL1 (0.42) | CTSSPSMB5L3MBTL1KLKB1CTSL | |
| SCHEMBL16305639 | 0.86 | L3MBTL1 (0.41) | CTSSL3MBTL1KLKB1CTSLKIFC1 | |
| SCHEMBL22384056 | 0.86 | L3MBTL1 (0.41) | CTSSL3MBTL1KLKB1CTSLKIFC1 | |
| SCHEMBL16305975 | 0.86 | CTSS (0.40) | CTSSL3MBTL1KLKB1DDR1MAPK14 | |
| SCHEMBL16305727 | 0.85 | KLKB1 (0.41) | CTSSPSMB1PSMB8PSMB9PSMB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3008056-B1 | NOVEL GLP-1 RECEPTOR MODULATORS | CELGENE INT II SARL (CH) | 2020-12-09 | — | — | EP | disclosed |
| EP-3230276-B1 | GLP-1 RECEPTOR MODULATORS | CELGENE INT II SARL (CH) | 2020-09-02 | — | — | EP | disclosed |