Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.30 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Maleic Acid SCHEMBL22721173 | 0.82 | TSHR (0.53) | ALDH1A1GLATP53MEN1KMT2A | |
| Fumaric Acid SCHEMBL28488073 | 0.82 | TSHR (0.53) | ALDH1A1GLATP53MEN1KMT2A | |
| Fumaric Acid SCHEMBL28262357 | 0.82 | TSHR (0.53) | ALDH1A1GLATP53MEN1KMT2A | |
| Maleic Acid SCHEMBL22721174 | 0.82 | TSHR (0.53) | ALDH1A1GLATP53MEN1KMT2A | |
| Fumaric Acid SCHEMBL10777530 | 0.82 | TSHR (0.53) | ALDH1A1GLATP53MEN1KMT2A | |
| Tetrahydrofuran SCHEMBL1950354 | 0.81 | — | — | |
| Tetrahydrofuran SCHEMBL3294902 | 0.81 | ALDH1A1 (0.61) | ALDH1A1GLATP53MEN1KMT2A | |
| Tetrahydrofuran SCHEMBL16166505 | 0.81 | ALDH1A1 (0.61) | ALDH1A1GLATP53MEN1KMT2A | |
| Tetrahydrofuran SCHEMBL905739 | 0.81 | ALDH1A1 (0.61) | ALDH1A1GLATP53MEN1KMT2A | |
| Tetrahydrofuran SCHEMBL246413 | 0.80 | LMNA (0.56) | ALDH1A1GLATP53MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011101861-A1 | PROCESS FOR PREPARATION OF DPP-IV INHIBITORS | MSN LABORATORIES LIMITED (IN) | 2011-08-25 | — | — | WO | disclosed |
| CN-1070856-C | Thiazole derivatives | OTSUDA PHARMACEUTICAL CO LTD (JP) | 2001-09-12 | — | — | CN | disclosed |
| CN-1198160-A | Thiazole derivative | OTSUKA PHARMA CO LTD (JP) | 1998-11-04 | — | — | CN | disclosed |