Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 8/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CCR1 | P32246 | 1/20 | 0.40 |
| ▸ | HRH2 | P25021 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.39 |
| ▸ | F13A1 | P00488 | 1/20 | 0.39 |
| ▸ | TGM2 | P21980 | 1/20 | 0.39 |
| ▸ | TGM1 | P22735 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | YAP1 | P46937 | 2/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17968796 | 1.00 | P2RX7 (0.43) | P2RX7KMT2ACCR1HRH2HRH1 | |
| SCHEMBL17834397 | 1.00 | P2RX7 (0.43) | P2RX7KMT2ACCR1HRH2HRH1 | |
| SCHEMBL17968795 | 1.00 | P2RX7 (0.43) | P2RX7KMT2ACCR1HRH2HRH1 | |
| SCHEMBL17968984 | 0.94 | CCR1 (0.42) | P2RX7CCR1ITGB3ITGA2BF13A1 | |
| SCHEMBL19465506 | 0.94 | CCR1 (0.42) | P2RX7CCR1ITGB3ITGA2BF13A1 | |
| SCHEMBL17834477 | 0.94 | CCR1 (0.42) | P2RX7CCR1ITGB3ITGA2BF13A1 | |
| SCHEMBL22384175 | 0.91 | CCR1 (0.42) | P2RX7CCR1ITGB3ITGA2BF13A1 | |
| SCHEMBL17834396 | 0.89 | CCR1 (0.42) | P2RX7CCR1ITGB3ITGA2BF13A1 | |
| SCHEMBL17968901 | 0.89 | ITGB3 (0.42) | P2RX7CCR1ITGB3ITGA2BYAP1 | |
| SCHEMBL17834702 | 0.89 | ITGB3 (0.42) | P2RX7CCR1ITGB3ITGA2BYAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3230276-B1 | GLP-1 RECEPTOR MODULATORS | CELGENE INT II SARL (CH) | 2020-09-02 | — | — | EP | disclosed |