Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.42 |
| ▸ | F13A1 | P00488 | 1/20 | 0.42 |
| ▸ | TGM2 | P21980 | 1/20 | 0.42 |
| ▸ | TGM1 | P22735 | 1/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 6/20 | 0.39 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.39 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 3/20 | 0.39 |
| ▸ | CTSL | P07711 | 2/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.38 |
| ▸ | ITGAV | P06756 | 2/20 | 0.38 |
| ▸ | FNTA | P49354 | 1/20 | 0.38 |
| ▸ | FNTB | P49356 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17834477 | 0.94 | CCR1 (0.42) | CCR1F13A1TGM2TGM1P2RX7 | |
| SCHEMBL17968984 | 0.94 | CCR1 (0.42) | CCR1F13A1TGM2TGM1P2RX7 | |
| SCHEMBL19465506 | 0.94 | CCR1 (0.42) | CCR1F13A1TGM2TGM1P2RX7 | |
| SCHEMBL17834396 | 0.92 | CCR1 (0.42) | CCR1F13A1TGM2TGM1P2RX7 | |
| SCHEMBL17834397 | 0.91 | P2RX7 (0.43) | CCR1F13A1TGM2TGM1P2RX7 | |
| SCHEMBL22384156 | 0.91 | P2RX7 (0.43) | CCR1F13A1TGM2TGM1P2RX7 | |
| SCHEMBL17968796 | 0.91 | P2RX7 (0.43) | CCR1F13A1TGM2TGM1P2RX7 | |
| SCHEMBL17968795 | 0.91 | P2RX7 (0.43) | CCR1F13A1TGM2TGM1P2RX7 | |
| SCHEMBL17968792 | 0.88 | ITGB3 (0.49) | CCR1ITGA4ITGB7ITGB3ITGA2B | |
| SCHEMBL17968791 | 0.88 | ITGB3 (0.49) | CCR1ITGA4ITGB7ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3230276-B1 | GLP-1 RECEPTOR MODULATORS | CELGENE INT II SARL (CH) | 2020-09-02 | — | — | EP | disclosed |