Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | CTSV | O60911 | 3/20 | 0.40 |
| ▸ | CTSL | P07711 | 3/20 | 0.40 |
| ▸ | CTSB | P07858 | 3/20 | 0.40 |
| ▸ | CTSS | P25774 | 3/20 | 0.40 |
| ▸ | CTSK | P43235 | 3/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.40 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.40 |
| ▸ | CCKBR | P32239 | 1/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.40 |
| ▸ | HPGDS | O60760 | 1/20 | 0.40 |
| ▸ | KIFC1 | Q9BW19 | 2/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20426087 | 0.92 | CTSL (0.42) | MAPTL3MBTL1CTSLCTSBCTSS | |
| SCHEMBL16305671 | 0.91 | GCGR (0.45) | NPC1RAB9ATP53MAPTSMN1; SMN2 | |
| SCHEMBL22384197 | 0.89 | MCHR1 (0.43) | L3MBTL1CTSLCTSBCTSSCTSK | |
| SCHEMBL19485578 | 0.85 | L3MBTL1 (0.41) | MAPTL3MBTL1CTSLCTSBCTSS | |
| SCHEMBL16305844 | 0.84 | GCGR (0.45) | L3MBTL1S1PR4S1PR1S1PR5S1PR3 | |
| SCHEMBL16305857 | 0.83 | GCGR (0.46) | L3MBTL1S1PR4S1PR1S1PR5S1PR3 | |
| SCHEMBL16305856 | 0.83 | GCGR (0.46) | MAPTL3MBTL1CTSLCTSBCTSS | |
| SCHEMBL19807148 | 0.83 | CTSL (0.42) | MAPTL3MBTL1CTSLCTSBCTSS | |
| SCHEMBL16305719 | 0.83 | GCGR (0.48) | MAPTL3MBTL1CTSLCTSBCTSS | |
| SCHEMBL16305720 | 0.82 | GCGR (0.45) | MAPTL3MBTL1CTSVCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3230276-B1 | GLP-1 RECEPTOR MODULATORS | CELGENE INT II SARL (CH) | 2020-09-02 | — | — | EP | disclosed |