Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HPGDS | O60760 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 5/20 | 0.40 |
| ▸ | CTSS | P25774 | 5/20 | 0.40 |
| ▸ | CTSB | P07858 | 4/20 | 0.40 |
| ▸ | CTSK | P43235 | 4/20 | 0.40 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.40 |
| ▸ | KIFC1 | Q9BW19 | 3/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.38 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.38 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16305658 | 0.92 | GCGR (0.45) | MCHR1L3MBTL1HPGDSCTSLCTSS | |
| SCHEMBL20426087 | 0.89 | CTSL (0.42) | L3MBTL1HPGDSCTSLCTSSCTSB | |
| SCHEMBL22384196 | 0.89 | NPC1 (0.41) | L3MBTL1HPGDSCTSLCTSSCTSB | |
| SCHEMBL16305662 | 0.84 | PLG (0.43) | MCHR1L3MBTL1KLKB1KIFC1S1PR1 | |
| SCHEMBL19485578 | 0.83 | L3MBTL1 (0.41) | L3MBTL1CTSLCTSSCTSBCTSK | |
| SCHEMBL16305663 | 0.83 | PLG (0.44) | L3MBTL1KLKB1KIFC1S1PR1 | |
| SCHEMBL16305856 | 0.82 | GCGR (0.46) | L3MBTL1HPGDSCTSLCTSSCTSB | |
| SCHEMBL16305719 | 0.82 | GCGR (0.48) | L3MBTL1CTSLCTSSCTSBCTSK | |
| SCHEMBL16305671 | 0.82 | GCGR (0.45) | L3MBTL1CTSLCTSSCTSBCTSK | |
| SCHEMBL16305720 | 0.81 | GCGR (0.45) | L3MBTL1CTSLCTSSCTSBCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3230276-B1 | GLP-1 RECEPTOR MODULATORS | CELGENE INT II SARL (CH) | 2020-09-02 | — | — | EP | disclosed |