Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 9/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.39 |
| ▸ | ITGAV | P06756 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | FNTA | P49354 | 1/20 | 0.37 |
| ▸ | FNTB | P49356 | 1/20 | 0.37 |
| ▸ | HRH2 | P25021 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17834418 | 1.00 | P2RX7 (0.43) | P2RX7ITGB3ITGAVKMT2AFNTA | |
| SCHEMBL17825441 | 0.93 | ITGB3 (0.42) | P2RX7ITGB3ITGAVFNTAFNTB | |
| SCHEMBL17968809 | 0.93 | ITGB3 (0.42) | P2RX7ITGB3ITGAVFNTAFNTB | |
| SCHEMBL17834535 | 0.84 | DPP4 (0.41) | HRH2HRH1 | |
| SCHEMBL17532278 | 0.83 | P2RX7 (0.52) | P2RX7ITGB3KMT2AHRH2HRH1 | |
| SCHEMBL16305994 | 0.83 | HRH2 (0.48) | P2RX7ITGB3ITGAVHRH2HRH1 | |
| SCHEMBL16294766 | 0.83 | HRH2 (0.48) | P2RX7ITGB3ITGAVHRH2HRH1 | |
| SCHEMBL17968795 | 0.81 | P2RX7 (0.43) | P2RX7ITGB3KMT2AHRH2HRH1 | |
| SCHEMBL22384156 | 0.81 | P2RX7 (0.43) | P2RX7ITGB3KMT2AHRH2HRH1 | |
| SCHEMBL17968796 | 0.81 | P2RX7 (0.43) | P2RX7ITGB3KMT2AHRH2HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3230276-B1 | GLP-1 RECEPTOR MODULATORS | CELGENE INT II SARL (CH) | 2020-09-02 | — | — | EP | disclosed |