Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | JAK3 | P52333 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22651671 | 0.76 | MBOAT4 (0.40) | PRMT5HRH3 | |
| SCHEMBL17825442 | 0.76 | DDB1 (0.42) | TLR8TLR7 | |
| Hydrochloric Acid SCHEMBL17825460 | 0.74 | DDB1 (0.41) | TLR8TLR7 | |
| SCHEMBL17825347 | 0.74 | DDB1 (0.56) | — | |
| SCHEMBL27196770 | 0.72 | HRH3 (0.43) | TLR8TLR7HRH3 | |
| Hydrochloric Acid SCHEMBL27196872 | 0.71 | HRH3 (0.42) | TLR8TLR7HRH3 | |
| SCHEMBL22502996 | 0.71 | QDPR (0.45) | DRD2TLR8TLR7PRMT5HRH3 | |
| SCHEMBL21285985 | 0.70 | SLC18A3 (0.49) | DRD2TLR8TLR7EGFRLCK | |
| SCHEMBL16994794 | 0.70 | SLC18A3 (0.49) | DRD2TLR8TLR7 | |
| SCHEMBL14245302 | 0.69 | ALDH1A1 (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3230276-B1 | GLP-1 RECEPTOR MODULATORS | CELGENE INT II SARL (CH) | 2020-09-02 | — | — | EP | disclosed |