Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | KDM1A | O60341 | 5/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | RCOR1 | Q9UKL0 | 2/20 | 0.44 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 2/20 | 0.43 |
| ▸ | HTR2B | P41595 | 2/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL916179 | 1.00 | TSHR (0.56) | TSHRSLC6A2SLC6A4SLC6A3KDM1A | |
| SCHEMBL83447 | 1.00 | TSHR (0.56) | TSHRSLC6A2SLC6A4SLC6A3KDM1A | |
| Methyl Alcohol SCHEMBL8767666 | 0.93 | TSHR (0.50) | TSHRSLC6A2SLC6A4SLC6A3KDM1A | |
| SCHEMBL46155 | 0.86 | TSHR (0.72) | TSHR | |
| SCHEMBL5853845 | 0.84 | TSHR (0.41) | TSHRSLC6A2SLC6A4SLC6A3KDM1A | |
| SCHEMBL8250970 | 0.83 | TSHR (0.40) | TSHRSLC6A2SLC6A4SLC6A3KDM1A | |
| SCHEMBL15348686 | 0.81 | SLC6A2 (0.46) | TSHRSLC6A2SLC6A4SLC6A3KDM1A | |
| SCHEMBL17548454 | 0.80 | SLC6A2 (0.48) | SLC6A2SLC6A4SLC6A3KDM1AKCNH2 | |
| SCHEMBL17548027 | 0.80 | KDM1A (0.38) | TSHRSLC6A2SLC6A4SLC6A3KDM1A | |
| SCHEMBL13606171 | 0.80 | SLC6A2 (0.45) | TSHRSLC6A2SLC6A4SLC6A3KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119662578-A | Styrene monooxygenase combined mutant and application thereof | 中国科学院成都生物研究所 | 2025-03-21 | — | — | CN | claimed |
| CN-115927276-B | Halohydrin dehalogenase mutant and application thereof in synthesis of chiral oxazolidinone | 中国科学院天津工业生物技术研究所 | 2024-08-27 | — | — | CN | claimed |
| CN-119662578-A | Styrene monooxygenase combined mutant and application thereof | 中国科学院成都生物研究所 | 2025-03-21 | — | — | CN | disclosed |
| CN-115927276-B | Halohydrin dehalogenase mutant and application thereof in synthesis of chiral oxazolidinone | 中国科学院天津工业生物技术研究所 | 2024-08-27 | — | — | CN | disclosed |
| CN-115927276-A | Halogen alcohol dehalogenase mutant and application thereof in synthesizing chiral oxazolidinone | 中国科学院天津工业生物技术研究所 | 2023-04-07 | — | — | CN | disclosed |
| US-20220162211-A1 | COMPOUNDS AND METHODS FOR THE TREATMENT OF PARASITIC DISEASES | THE BROAD INSTITUTE, INC. (US) | 2022-05-26 | — | — | US | disclosed |
| US-11174260-B2 | Compounds and methods for the treatment of parasitic diseases | THE BROAD INSTITUTE, INC. (US) | 2021-11-16 | — | — | US | disclosed |
| US-20160289235-A1 | COMPOUNDS AND METHODS FOR THE TREATMENT OF MALARIA | THE BROAD INSTITUTE, INC. (US) | 2016-10-06 | — | — | US | disclosed |
| US-20150164888-A1 | CYCLOPROPYL AMIDE DERIVATIVES | ASTRAZENECA AB (SE) | 2015-06-18 | — | — | US | disclosed |
| US-20150164889-A1 | CYCLOPROPYL AMIDE DERIVATIVES | ASTRAZENECA AB (SE) | 2015-06-18 | — | — | US | disclosed |
| US-20150164888-A1 | CYCLOPROPYL AMIDE DERIVATIVES | ASTRAZENECA AB (SE) | 2015-06-18 | — | — | US | disclosed |
| US-7432258-B2 | Morpholinyl and pyrrolidinyl analogs | SMITHKLINE BEECHAM CORPORATION (US) | 2008-10-07 | — | — | US | disclosed |
| US-7432258-B2 | Morpholinyl and pyrrolidinyl analogs | SMITHKLINE BEECHAM CORPORATION (US) | 2008-10-07 | — | — | US | disclosed |
| US-7432258-B2 | Morpholinyl and pyrrolidinyl analogs | SMITHKLINE BEECHAM CORPORATION (US) | 2008-10-07 | — | — | US | disclosed |
| WO-2008064817-A2 | METHOD FOR THE STEREOSELECTIVE SYNTHESIS OF CHIRAL EPOXIDES BY ADH REDUCTION OF KETONES SUBSTITUTED WITH ALPHA STARTING GROUPS AND CYCLISATION | ARCHIMICA GMBH (DE) | 2008-06-05 | — | — | WO | disclosed |
| WO-2008011551-A1 | MORPHOLINYL AND PYRROLIDINYL ANALOGS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-01-24 | — | — | WO | disclosed |
| WO-2008011551-A1 | MORPHOLINYL AND PYRROLIDINYL ANALOGS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-01-24 | — | — | WO | disclosed |
| US-20080021023-A1 | 4'-[(1R)-1-[[(6,7-dichloro-3-oxo-2,3-dihydro-4H-1,4-benzoxazin- 4-yl)acetyl](methyl)amino]-2-(4-morpholinyl)ethyl]-4-biphenylcarboxylic acid; as antagonists of urotensin II, congestive heart failure, stroke, ischemic heart disease (e.g. angina, myocardial ischemia), cardiac arrhythmia, hypertension | GLAXOSMITHKLINE LLC | 2008-01-24 | — | — | US | disclosed |
| US-20080021023-A1 | 4'-[(1R)-1-[[(6,7-dichloro-3-oxo-2,3-dihydro-4H-1,4-benzoxazin- 4-yl)acetyl](methyl)amino]-2-(4-morpholinyl)ethyl]-4-biphenylcarboxylic acid; as antagonists of urotensin II, congestive heart failure, stroke, ischemic heart disease (e.g. angina, myocardial ischemia), cardiac arrhythmia, hypertension | GLAXOSMITHKLINE LLC | 2008-01-24 | — | — | US | disclosed |
| US-20080021023-A1 | 4'-[(1R)-1-[[(6,7-dichloro-3-oxo-2,3-dihydro-4H-1,4-benzoxazin- 4-yl)acetyl](methyl)amino]-2-(4-morpholinyl)ethyl]-4-biphenylcarboxylic acid; as antagonists of urotensin II, congestive heart failure, stroke, ischemic heart disease (e.g. angina, myocardial ischemia), cardiac arrhythmia, hypertension | GLAXOSMITHKLINE LLC | 2008-01-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160289235-A1 | COMPOUNDS AND METHODS FOR THE TREATMENT OF MALARIA | G6PD, CYP11B2, GLS2 | TSHR 3225/4885SLC6A2 1518/4885SLC6A4 3141/4885 |
| US-20150164888-A1 | CYCLOPROPYL AMIDE DERIVATIVES | HRH4, HRH2, HRH3 | TSHR 291/4885SLC6A2 1674/4885SLC6A4 1367/4885 |
| US-20220162211-A1 | COMPOUNDS AND METHODS FOR THE TREATMENT OF PARASITIC DISEASES | PIGO, CAT, OAT | TSHR 4432/4885SLC6A2 1490/4885SLC6A4 2155/4885 |
| US-20150164889-A1 | CYCLOPROPYL AMIDE DERIVATIVES | HRH4, HRH2, HRH3 | TSHR 291/4885SLC6A2 1674/4885SLC6A4 1367/4885 |
| US-20080021023-A1 | 4'-[(1R)-1-[[(6,7-dichloro-3-oxo-2,3-dihydro-4H-1,4-benzoxazin- 4-yl)acetyl](methyl)amino]-2-(4-morpholinyl)ethyl]-4-biphenylcarboxylic acid; as antagonists of urotensin II, congestive heart failure, stroke, ischemic heart disease (e.g. angina, myocardial ischemia), cardiac arrhythmia, hypertension | UTS2R, PLAUR, FABP3 | TSHR 2508/4885SLC6A2 3706/4885SLC6A4 3322/4885 |
| US-11174260-B2 | Compounds and methods for the treatment of parasitic diseases | PIGO, CAT, OAT | TSHR 4432/4885SLC6A2 1490/4885SLC6A4 2155/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.