SCHEMBL22385137

SCHEMBL22385137

OC1OCC(COCC(F)(F)F)O1

nearest known ligand 0.44

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.44
MAPK1 P28482 1/20 0.44
ALDH1A1 P00352 3/20 0.34
SMN1; SMN2 Q16637 1/20 0.32
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21104090 0.83 TSHR (0.47) TSHRMAPK1ALDH1A1SMN1; SMN2TDP1
SCHEMBL2547812 0.82 TSHR (0.61) TSHRMAPK1ALDH1A1SMN1; SMN2TDP1
SCHEMBL18290484 0.82 TSHR (0.61) TSHRMAPK1ALDH1A1SMN1; SMN2TDP1
SCHEMBL16854634 0.82 TSHR (0.61) TSHRMAPK1ALDH1A1SMN1; SMN2TDP1
SCHEMBL28119256 0.81 TSHR (0.59) TSHRMAPK1ALDH1A1SMN1; SMN2TDP1
SCHEMBL14003906 0.76 SMN1; SMN2 (0.42) TSHRMAPK1ALDH1A1SMN1; SMN2TDP1
SCHEMBL85888 0.71 TSHR (0.57) TSHRMAPK1ALDH1A1SMN1; SMN2TDP1
SCHEMBL7640985 0.71 TSHR (0.42) TSHRMAPK1ALDH1A1SMN1; SMN2TDP1
SCHEMBL14003903 0.70 SMN1; SMN2 (0.70) TSHRMAPK1ALDH1A1SMN1; SMN2TDP1
SCHEMBL28833181 0.70 TSHR (0.43) TSHRMAPK1ALDH1A1SMN1; SMN2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3703173-A1 ELECTROLYTIC SOLUTION, ELECTROCHEMICAL DEVICE, LITHIUM ION SECONDARY BATTERY, AND MODULE Daikin Industries, Ltd. (JP) 2020-09-02 EP disclosed