Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14961439 | 0.90 | LMNA (0.42) | TSHRMAPK1LMNAPOLBALDH1A1 | |
| SCHEMBL14961437 | 0.88 | LMNA (0.38) | TSHRMAPK1SMN1; SMN2LMNAPOLB | |
| SCHEMBL16854634 | 0.82 | TSHR (0.61) | TSHRMAPK1SMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL18290484 | 0.82 | TSHR (0.61) | TSHRMAPK1SMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL2547812 | 0.82 | TSHR (0.61) | TSHRMAPK1SMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL5094637 | 0.80 | TSHR (0.37) | TSHRMAPK1 | |
| SCHEMBL28119256 | 0.80 | TSHR (0.59) | TSHRMAPK1SMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL1195725 | 0.78 | TSHR (0.48) | TSHRMAPK1SMN1; SMN2LMNAPOLB | |
| SCHEMBL28492560 | 0.77 | TSHR (0.55) | TSHRMAPK1SMN1; SMN2LMNAPOLB | |
| SCHEMBL14961482 | 0.75 | LMNA (0.40) | TSHRMAPK1SMN1; SMN2LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6417314-B1 | WEAR RESISTANCE, TEAR AND BONDING STRENGTH; COATINGS, PLASTICS | AEROJET-GENERAL CORPORATION | 2002-07-09 | — | — | US | disclosed |
| US-6037483-A | CHARGING REACTION VESSEL WITH AQUEOUS MIXTURE OF MONO-SUBSTITURED OXETANE, FLUOROALCOHOL, PHASE TRANSFER CATALYST AND STRONG BASE TO FORM REACTION MIXTURE; HEATING UNTIL REACTION IS COMPLETE | AEROJET-GENERAL CORPORATION (US) | 2000-03-14 | — | — | US | disclosed |