Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN7A | Q01118 | 4/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 4/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 11/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 4/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22386184 | 0.78 | SCN7A (0.41) | SCN7ASCN5ASCN9ALRRK2MGLL | |
| SCHEMBL19848029 | 0.76 | SCN9A (0.41) | SCN7ASCN5ASCN9ALRRK2SLC6A9 | |
| SCHEMBL19847947 | 0.69 | SCN9A (0.38) | SCN9A | |
| SCHEMBL19847955 | 0.68 | PARP10 (0.34) | SCN9A | |
| SCHEMBL19848051 | 0.67 | LRRK2 (0.31) | LRRK2 | |
| SCHEMBL22386185 | 0.67 | HTR1A (0.40) | MGLL | |
| SCHEMBL22386242 | 0.67 | FFAR1 (0.34) | SCN9ALRRK2 | |
| SCHEMBL22386193 | 0.65 | RBP4 (0.35) | SCN7ASCN5ASCN9AMGLL | |
| SCHEMBL19847869 | 0.65 | ACACB (0.34) | SCN7ASCN5ASCN9ALRRK2SLC6A9 | |
| SCHEMBL19848001 | 0.65 | F10 (0.43) | SCN7ASCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3279191-B1 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICALS CO (JP) | 2020-09-02 | — | — | EP | disclosed |