Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN7A | Q01118 | 5/20 | 0.41 |
| ▸ | SCN5A | Q14524 | 5/20 | 0.41 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.39 |
| ▸ | SLC6A9 | P48067 | 3/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 4/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | ABL2 | P42684 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 2/20 | 0.35 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22386262 | 0.78 | SCN7A (0.38) | SCN7ASCN5ASLC6A9LRRK2SCN9A | |
| SCHEMBL19848029 | 0.77 | SCN9A (0.41) | SCN7ASCN5ASLC6A9LRRK2SCN9A | |
| SCHEMBL22386185 | 0.75 | HTR1A (0.40) | TRPV4MGLL | |
| SCHEMBL22386193 | 0.75 | RBP4 (0.35) | SCN7ASCN5ASCN9AMGLL | |
| SCHEMBL19833922 | 0.74 | MGLL (0.58) | TRPV4MGLL | |
| SCHEMBL19847972 | 0.74 | RBP4 (0.34) | SCN7ASCN5ASCN9A | |
| SCHEMBL19847944 | 0.73 | MGLL (0.46) | SCN7ASCN5ATRPV4SLC6A9KCNH2 | |
| SCHEMBL19834015 | 0.70 | GPR119 (0.51) | TRPV4SCN9A | |
| SCHEMBL19847947 | 0.69 | SCN9A (0.38) | SCN9A | |
| SCHEMBL21984779 | 0.69 | NOS1 (0.54) | TRPV4ABL1SRCABL2EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3279191-B1 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICALS CO (JP) | 2020-09-02 | — | — | EP | disclosed |