Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | CASP3 | P42574 | 1/20 | 0.30 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.30 |
| ▸ | RELA | Q04206 | 1/20 | 0.30 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.30 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.30 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22386468 | 0.95 | GPR3 (0.33) | GPR3NPC1RAB9AKDM4EGAA | |
| SCHEMBL22386452 | 0.92 | — | — | |
| SCHEMBL22386436 | 0.90 | GPR3 (0.33) | GPR3NPC1RAB9AKDM4EGAA | |
| SCHEMBL22386456 | 0.89 | POLB (0.36) | GPR3KDM4EKMT2AMEN1TDP1 | |
| SCHEMBL22386457 | 0.86 | — | — | |
| SCHEMBL22386464 | 0.86 | — | — | |
| SCHEMBL22386438 | 0.84 | NPC1 (0.37) | GPR3NPC1RAB9AKDM4EGAA | |
| SCHEMBL22386423 | 0.79 | POLB (0.39) | GPR3KDM4EGAAKMT2AMEN1 | |
| SCHEMBL22386421 | 0.77 | NPC1 (0.37) | GPR3NPC1RAB9AKDM4EGAA | |
| SCHEMBL22386453 | 0.74 | MAOB (0.33) | GPR3HPGDKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11021489-B2 | Polycyclic aromatic compound embodiments and methods of making and using the same | UNIVERSITY OF OREGON (US) | 2021-06-01 | — | — | US | disclosed |
| US-20200277302-A1 | POLYCYCLIC AROMATIC COMPOUND EMBODIMENTS AND METHODS OF MAKING AND USING THE SAME | UNIVERSITY OF OREGON (US) | 2020-09-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200277302-A1 | POLYCYCLIC AROMATIC COMPOUND EMBODIMENTS AND METHODS OF MAKING AND USING THE SAME | AHR, EED, ARNT | GPR3 1589/4885NPC1 4322/4885RAB9A 4423/4885 |
| US-11021489-B2 | Polycyclic aromatic compound embodiments and methods of making and using the same | AHR, EED, ARNT | GPR3 1589/4885NPC1 4322/4885RAB9A 4423/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.