Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | GPR3 | P46089 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | TACR1 | P25103 | 3/20 | 0.30 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
| ▸ | RORB | Q92753 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22386440 | 0.90 | MAPT (0.34) | MAOBGPR3MEN1KMT2ACYP1A2 | |
| SCHEMBL22386517 | 0.85 | SLC9A1 (0.30) | — | |
| SCHEMBL22386510 | 0.85 | CYP1A1 (0.31) | CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL22386488 | 0.83 | GPR3 (0.36) | MAOBGPR3 | |
| SCHEMBL22386460 | 0.81 | — | — | |
| SCHEMBL22386459 | 0.81 | — | — | |
| SCHEMBL22386438 | 0.80 | NPC1 (0.37) | GPR3MEN1KMT2AHPGDNPSR1 | |
| SCHEMBL22386507 | 0.74 | GPR3 (0.33) | GPR3MEN1KMT2AHPGD | |
| SCHEMBL22386441 | 0.73 | GPR3 (0.36) | MAOBGPR3 | |
| SCHEMBL22386456 | 0.72 | POLB (0.36) | GPR3MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11021489-B2 | Polycyclic aromatic compound embodiments and methods of making and using the same | UNIVERSITY OF OREGON (US) | 2021-06-01 | — | — | US | disclosed |
| US-20200277302-A1 | POLYCYCLIC AROMATIC COMPOUND EMBODIMENTS AND METHODS OF MAKING AND USING THE SAME | UNIVERSITY OF OREGON (US) | 2020-09-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200277302-A1 | POLYCYCLIC AROMATIC COMPOUND EMBODIMENTS AND METHODS OF MAKING AND USING THE SAME | AHR, EED, ARNT | MAOB 1624/4885GPR3 1589/4885MEN1 1104/4885 |
| US-11021489-B2 | Polycyclic aromatic compound embodiments and methods of making and using the same | AHR, EED, ARNT | MAOB 1624/4885GPR3 1589/4885MEN1 1104/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.