SCHEMBL22386856

SCHEMBL22386856

CC1(C)c2ccccc2-c2ccc(-n3c4ccccc4c4ccc(-c5nc(-c6ccc(-c7ccccc7)cc6)nc(-c6ccc(-c7ccc(-c8ccccc8)cc7)cc6)n5)cc43)cc21

nearest known ligand 0.34

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 1/20 0.33
▸ ATM Q13315 1/20 0.33
▸ L3MBTL1 Q9Y468 1/20 0.33
▸ HDAC4 P56524 1/20 0.32
▸ RXRA P19793 1/20 0.32
▸ RXRB P28702 1/20 0.32
▸ PDK2 Q15119 1/20 0.30
▸ AVPR1A P37288 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22386934 1.00 KDM4E (0.33) KDM4EATML3MBTL1HDAC4RXRA
SCHEMBL22386869 1.00 KDM4E (0.33) KDM4EATML3MBTL1HDAC4RXRA
SCHEMBL22387014 1.00 KDM4E (0.33) KDM4EATML3MBTL1HDAC4RXRA
SCHEMBL22386850 0.99 L3MBTL1 (0.33) KDM4EATML3MBTL1HDAC4RXRA
SCHEMBL22386818 0.98 RXRA (0.34) KDM4EATML3MBTL1HDAC4RXRA
SCHEMBL24273010 0.97 HDAC4 (0.31) KDM4EATML3MBTL1HDAC4RXRA
SCHEMBL24273004 0.97 RXRA (0.32) KDM4EATML3MBTL1HDAC4RXRA
SCHEMBL22387004 0.97 RXRA (0.32) KDM4EATML3MBTL1HDAC4RXRA
SCHEMBL24273003 0.97 RXRA (0.32) KDM4EATML3MBTL1HDAC4RXRA
SCHEMBL22386969 0.97 RXRA (0.32) KDM4EATML3MBTL1HDAC4RXRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11708356-B2 Organic electroluminescent materials and devices Beijing Summer Sprout Technology Co., Ltd. (CN) 2023-07-25 — — US disclosed
US-11708356-B2 Organic electroluminescent materials and devices Beijing Summer Sprout Technology Co., Ltd. (CN) 2023-07-25 — — US disclosed
US-20200277283-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Beijing Summer Sprout Technology Co., Ltd. (CN) 2020-09-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11708356-B2 Organic electroluminescent materials and devices VDAC3, VDAC2, VDAC1 KDM4E 1338/4885ATM 4014/4885L3MBTL1 333/4885
US-20200277283-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES VDAC3, VDAC2, VDAC1 KDM4E 1338/4885ATM 4014/4885L3MBTL1 333/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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