SCHEMBL22389126

SCHEMBL22389126

CC1(C)c2cc(N(c3ccc4c(c3)C(C)(C)c3cc(-c5ccccc5)c5oc6ccccc6c5c3-4)c3ccccc3-c3ccccc3)ccc2-c2c1cc(-c1ccccc1)c1oc3ccccc3c21

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ CDC14B O60729 2/20 0.34
▸ CDC14A Q9UNH5 2/20 0.34
▸ ALK Q9UM73 8/20 0.34
▸ MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20927692 0.95 CDC14B (0.32) CDC14BCDC14AALKMAPT
SCHEMBL20927632 0.94 CDC14B (0.37) CDC14BCDC14AALKMAPT
SCHEMBL25815424 0.93 CDC14B (0.31) CDC14BCDC14AALK
SCHEMBL22388899 0.93 MAPT (0.32) CDC14BCDC14AALKMAPT
SCHEMBL22388979 0.93 ALOX5 (0.38) CDC14BCDC14AALK
SCHEMBL20927752 0.93 CDC14B (0.34) CDC14BCDC14AALKMAPT
SCHEMBL24474771 0.93 CDC14B (0.31) CDC14BCDC14AALK
SCHEMBL20927698 0.93 ALK (0.31) CDC14BCDC14AALK
SCHEMBL22389195 0.93 CDC14B (0.32) CDC14BCDC14AALK
SCHEMBL21785217 0.93 CDC14B (0.31) CDC14BCDC14AALK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11578063-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2023-02-14 — — US disclosed
US-20200277284-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2020-09-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200277284-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES L1CAM, EFNA1, EPCAM CDC14B 4597/4885CDC14A 4518/4885ALK 2858/4885
US-11578063-B2 Materials for organic electroluminescent devices GPX1, EPCAM, EFNA1 CDC14B 4688/4885CDC14A 4632/4885ALK 2189/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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