SCHEMBL22389195

SCHEMBL22389195

CC(C)(C)c1ccc(-c2cc3c(c4c2oc2ccccc24)-c2ccc(N(c4ccc5c(c4)C(C)(C)c4cc(-c6ccc(C(C)(C)C)cc6)c6oc7ccccc7c6c4-5)c4ccccc4-c4ccccc4)cc2C3(C)C)cc1

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ CDC14B O60729 3/20 0.32
▸ CDC14A Q9UNH5 3/20 0.32
▸ GPR84 Q9NQS5 1/20 0.32
▸ ALK Q9UM73 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21790917 0.94 — —
SCHEMBL24580736 0.94 — —
SCHEMBL22388900 0.93 ALDH1A1 (0.32) CDC14BCDC14AGPR84
SCHEMBL20927710 0.93 CDC14B (0.34) CDC14BCDC14AGPR84ALK
SCHEMBL22389126 0.93 CDC14B (0.34) CDC14BCDC14AALK
SCHEMBL22389198 0.92 GPR84 (0.32) CDC14BCDC14AGPR84ALK
SCHEMBL22389220 0.92 CDC14B (0.33) CDC14BCDC14A
SCHEMBL20927694 0.92 GPR84 (0.33) CDC14BCDC14AGPR84ALK
SCHEMBL22389160 0.90 MAPT (0.36) CDC14BCDC14AGPR84
SCHEMBL22389128 0.90 CDC14B (0.33) CDC14BCDC14AGPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230225195-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PERFORMANCE MATERIALS GERMANY GMBH (DE) 2023-07-13 — — US disclosed
US-20230225195-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PERFORMANCE MATERIALS GERMANY GMBH (DE) 2023-07-13 — — US disclosed
US-11578063-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2023-02-14 — — US disclosed
US-20200277284-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2020-09-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200277284-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES L1CAM, EFNA1, EPCAM CDC14B 4597/4885CDC14A 4518/4885GPR84 4089/4885
US-11578063-B2 Materials for organic electroluminescent devices GPX1, EPCAM, EFNA1 CDC14B 4688/4885CDC14A 4632/4885GPR84 4056/4885
US-20230225195-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES H1-0, H1-2, H1-4 CDC14B 4847/4885CDC14A 4797/4885GPR84 2690/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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