Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.44 |
| ▸ | ANPEP | P15144 | 7/20 | 0.38 |
| ▸ | RNPEP | Q9H4A4 | 2/20 | 0.38 |
| ▸ | DNPEP | Q9ULA0 | 2/20 | 0.38 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.35 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.35 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | LAP3 | P28838 | 3/20 | 0.31 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12214542 | 0.85 | SLC7A5 (0.50) | SLC7A5ANPEPRNPEPDNPEPSLC1A3 | |
| SCHEMBL22392056 | 0.84 | CHRNB2 (0.33) | CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL13144609 | 0.82 | SLC7A5 (0.56) | SLC7A5ANPEPRNPEPDNPEPSLC1A3 | |
| SCHEMBL21283383 | 0.81 | SLC7A5 (0.47) | SLC7A5ANPEPRNPEPDNPEPSLC1A3 | |
| SCHEMBL22392171 | 0.79 | ALOX15 (0.44) | CHRNB2CHRNA4CHRNB4CHRNA3DPP4 | |
| SCHEMBL14095412 | 0.79 | SLC7A5 (0.52) | SLC7A5ANPEPRNPEPDNPEPSLC1A3 | |
| SCHEMBL7647620 | 0.79 | SLC7A5 (0.52) | SLC7A5ANPEPRNPEPDNPEPSLC1A3 | |
| SCHEMBL28435189 | 0.79 | SLC7A5 (0.44) | SLC7A5ANPEPRNPEPDNPEPSLC1A3 | |
| SCHEMBL21264570 | 0.79 | SLC7A5 (0.44) | SLC7A5ANPEPRNPEPDNPEPSLC1A3 | |
| SCHEMBL22392070 | 0.78 | GSR (0.46) | RNPEPDPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11530298-B2 | Poly(phosphoesters) for delivery of nucleic acids | TRANSLATE BIO, INC. (US) | 2022-12-20 | — | — | US | disclosed |
| US-20200277446-A1 | POLY(PHOSPHOESTERS) FOR DELIVERY OF NUCLEIC ACIDS | TRANSLATE BIO, INC. | 2020-09-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200277446-A1 | POLY(PHOSPHOESTERS) FOR DELIVERY OF NUCLEIC ACIDS | POLR2E, POLR2H, POLR1A | SLC7A5 1781/4885ANPEP 2014/4885RNPEP 531/4885 |
| US-11530298-B2 | Poly(phosphoesters) for delivery of nucleic acids | POLR2E, POLR2H, POLR1A | SLC7A5 1781/4885ANPEP 2014/4885RNPEP 531/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.