SCHEMBL22392102

SCHEMBL22392102

CCn1cncc1Cn1c(CCl)nc2ccc(C(=O)OC(C)(C)C)cc21

nearest known ligand 0.44

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 9/20 0.44
▸ ACSS2 Q9NR19 4/20 0.38
▸ PPARG P37231 1/20 0.37
▸ AGTR1 P30556 1/20 0.35
▸ AGTR2 P50052 1/20 0.35
▸ BRD4 O60885 1/20 0.34
▸ HTR7 P34969 1/20 0.33
▸ HTR6 P50406 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30740718 0.90 ACSS2 (0.46) GLP1RACSS2PPARGHTR7HTR6
SCHEMBL24265338 0.90 ACSS2 (0.46) GLP1RACSS2PPARGHTR7HTR6
SCHEMBL26483189 0.86 GLP1R (0.45) GLP1RACSS2PPARGAGTR1AGTR2
SCHEMBL29945993 0.83 ACSS2 (0.41) GLP1RACSS2HTR7HTR6
SCHEMBL29826815 0.81 ACSS2 (0.46) GLP1RACSS2PPARGHTR7HTR6
SCHEMBL30740795 0.81 ACSS2 (0.46) GLP1RACSS2PPARGHTR7HTR6
SCHEMBL29826194 0.80 GLP1R (0.47) GLP1RACSS2
SCHEMBL30740742 0.80 GLP1R (0.47) GLP1RACSS2
SCHEMBL26039107 0.79 ACSS2 (0.43) ACSS2BRD4
SCHEMBL22932918 0.79 GLP1R (0.42) GLP1RACSS2PPARGAGTR1AGTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260035362-A1 GLP-1R AGONISTS AND USES THEREOF QILU REGOR THERAPEUTICS INC (CN) 2026-02-05 — — US disclosed
US-12365670-B2 GLP-IR agonists and uses thereof QILU REGOR THERAPEUTICS INC. (CN) 2025-07-22 — — US disclosed
US-20220024901-A1 GLP-1R AGONISTS AND USES THEREOF QILU REGOR THERAPEUTICS INC. (CN) 2022-01-27 — — US disclosed
US-20220024901-A1 GLP-1R AGONISTS AND USES THEREOF QILU REGOR THERAPEUTICS INC. (CN) 2022-01-27 — — US disclosed
US-10844049-B2 GLP-1R agonists and uses thereof QILU REGOR THERAPEUTICS INC. (CN) 2020-11-24 — — US disclosed
US-10844049-B2 GLP-1R agonists and uses thereof QILU REGOR THERAPEUTICS INC. (CN) 2020-11-24 — — US disclosed
US-20200283424-A1 GLP-1R AGONISTS AND USES THEREOF QILU REGOR THERAPEUTICS INC. (CN) 2020-09-10 — — US disclosed
US-20200283424-A1 GLP-1R AGONISTS AND USES THEREOF QILU REGOR THERAPEUTICS INC. (CN) 2020-09-10 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260035362-A1 GLP-1R AGONISTS AND USES THEREOF GLP1R, GPR119, IAPP GLP1R 1/4885ACSS2 2795/4885PPARG 365/4885
US-10844049-B2 GLP-1R agonists and uses thereof GLP1R, GPR119, GIPR GLP1R 1/4885ACSS2 1035/4885PPARG 50/4885
US-12365670-B2 GLP-IR agonists and uses thereof GLP1R, GPR119, GIPR GLP1R 1/4885ACSS2 751/4885PPARG 27/4885
US-20200283424-A1 GLP-1R AGONISTS AND USES THEREOF GLP1R, GPR119, GIPR GLP1R 1/4885ACSS2 1035/4885PPARG 50/4885
US-20220024901-A1 GLP-1R AGONISTS AND USES THEREOF GLP1R, GPR119, GIPR GLP1R 1/4885ACSS2 862/4885PPARG 21/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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