Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.41 |
| ▸ | GLP1R | P43220 | 8/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24265338 | 0.91 | ACSS2 (0.46) | ACSS2GLP1RDRD2TBXA2RLCK | |
| SCHEMBL30740718 | 0.91 | ACSS2 (0.46) | ACSS2GLP1RDRD2TBXA2RLCK | |
| SCHEMBL31159736 | 0.85 | GLP1R (0.45) | ACSS2GLP1RDRD2TBXA2RLCK | |
| SCHEMBL20266537 | 0.85 | GLP1R (0.45) | ACSS2GLP1RDRD2TBXA2RLCK | |
| SCHEMBL30686438 | 0.85 | GLP1R (0.41) | ACSS2GLP1RDRD2TBXA2RLCK | |
| SCHEMBL27111057 | 0.85 | GLP1R (0.41) | ACSS2GLP1RDRD2TBXA2RLCK | |
| Hydrochloric Acid SCHEMBL30269640 | 0.84 | GLP1R (0.44) | ACSS2GLP1RDRD2TBXA2RLCK | |
| Hydrochloric Acid SCHEMBL28910361 | 0.84 | GLP1R (0.44) | ACSS2GLP1RDRD2TBXA2RLCK | |
| SCHEMBL29945919 | 0.83 | DRD2 (0.40) | ACSS2GLP1RDRD2TBXA2RLCK | |
| SCHEMBL22392102 | 0.83 | GLP1R (0.44) | ACSS2GLP1RHTR7HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022184849-A1 | GLP-1R AGONISTS, USES AND PHARMACEUTICAL COMPOSITIONS THEREOF | LES LABORATOIRES SERVIER (FR) | 2022-09-09 | — | — | WO | disclosed |