Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.61 |
| ▸ | NOS1 | P29475 | 1/20 | 0.61 |
| ▸ | NOS2 | P35228 | 1/20 | 0.61 |
| ▸ | PI4KA | P42356 | 1/20 | 0.61 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.61 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.61 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CCR1 | P32246 | 1/20 | 0.33 |
| ▸ | CCR5 | P51681 | 1/20 | 0.33 |
| ▸ | CCR8 | P51685 | 1/20 | 0.33 |
| ▸ | METAP1 | P53582 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2-Aminopyridine SCHEMBL2775240 | 0.78 | — | — | |
| 2-Aminopyridine SCHEMBL9064720 | 0.78 | NOS3 (1.00) | NOS3NOS1NOS2PI4KAPI4K2B | |
| 2-Aminopyridine SCHEMBL29392931 | 0.78 | — | — | |
| Amitrole SCHEMBL788110 | 0.78 | HSP90AA1 (0.33) | HSP90AA1 | |
| 2-Aminopyridine SCHEMBL17844 | 0.78 | — | — | |
| Amitrole SCHEMBL44637 | 0.78 | — | — | |
| 2-Aminopyridine SCHEMBL5776523 | 0.77 | NOS3 (0.84) | NOS3NOS1NOS2PI4KAPI4K2B | |
| 2-Aminopyridine SCHEMBL70318 | 0.76 | — | — | |
| 2-Aminopyridine SCHEMBL8135890 | 0.76 | NOS3 (0.94) | NOS3NOS1NOS2PI4KAPI4K2B | |
| Amitrole SCHEMBL8468142 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9159542-B2 | Apparatus and method for inhibiting ionization source filament failure | THERMO FINNIGAN LLC (US) | 2015-10-13 | — | — | US | claimed |
| US-20130214147-A1 | Apparatus and Method for Inhibiting Ionization Source Filament Failure | THERMO FINNIGAN LLC | 2013-08-22 | — | — | US | claimed |
| EP-2529388-B1 | FRAGMENTATION REAGENTS FOR MASS SPECTROMETRY | MICROMASS LTD (GB) | 2019-10-23 | — | — | EP | disclosed |
| US-9159542-B2 | Apparatus and method for inhibiting ionization source filament failure | THERMO FINNIGAN LLC (US) | 2015-10-13 | — | — | US | disclosed |
| US-20130214147-A1 | Apparatus and Method for Inhibiting Ionization Source Filament Failure | THERMO FINNIGAN LLC | 2013-08-22 | — | — | US | disclosed |
| US-20130122599-A1 | Fragmentation Reagents For Mass Spectrometry | MICROMASS UK LIMITED (GB) | 2013-05-16 | — | — | US | disclosed |
| EP-2529388-A1 | FRAGMENTATION REAGENTS FOR MASS SPECTROMETRY | Micromass UK Limited (GB) | 2012-12-05 | — | — | EP | disclosed |
| WO-2011092515-A1 | FRAGMENTATION REAGENTS FOR MASS SPECTROMETRY | MICROMASS UK LIMITED (GB) | 2011-08-04 | — | — | WO | disclosed |