SCHEMBL2239233

SCHEMBL2239233

[c]1ccc2c(c1)Sc1[c]cccc1N2

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOX1 Q9Y5S8 8/20 0.42
GAA P10253 4/20 0.42
MAPT P10636 4/20 0.42
BCHE P06276 2/20 0.42
ACHE P22303 2/20 0.42
SNCA P37840 2/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
TDP1 Q9NUW8 2/20 0.42
CYP1A2 P05177 1/20 0.42
POLB P06746 1/20 0.42
CYP3A4 P08684 1/20 0.42
ADORA3 P0DMS8 1/20 0.42
ALOX15 P16050 1/20 0.42
ALOX12 P18054 1/20 0.42
MAOA P21397 1/20 0.42
CNR1 P21554 1/20 0.42
PTGS1 P23219 1/20 0.42
SLC6A2 P23975 1/20 0.42
HTR2C P28335 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25458 0.86 NOX1 (0.59) NOX1GAAMAPTBCHEACHE
SCHEMBL25692 0.80 NOX1 (0.68) NOX1GAAMAPTBCHEACHE
SCHEMBL17418130 0.80 GAA (0.41) NOX1GAAMAPTBCHEACHE
SCHEMBL852792 0.80 NOX1 (0.52) NOX1GAAMAPTBCHEACHE
SCHEMBL2237156 0.73 NOX1 (0.50) NOX1GAAMAPTBCHEACHE
SCHEMBL24088 0.72 NOX1 (0.65) NOX1GAAMAPTBCHEACHE
Phenothiazine SCHEMBL17006488 0.65 NOX1 (0.94) NOX1GAAMAPTBCHEACHE
SCHEMBL4651 0.65 NOX1 (0.59) NOX1GAAMAPTBCHEACHE
SCHEMBL132265 0.64 MAOA (0.36) NOX1GAAMAPTBCHEACHE
SCHEMBL1335326 0.64 NOX1 (0.46) NOX1GAAMAPTBCHEACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110309341-A1 AMINE POLYMER COMPOUND AND LIGHT EMITTING DEVICE USING THE SAME SUMATION CO., LTD. (JP) 2011-12-22 US disclosed
EP-2360201-A1 AMINE POLYMER COMPOUND AND LIGHT-EMITTING ELEMENT USING SAME Sumitomo Chemical Company, Limited (JP) 2011-08-24 EP disclosed
US-20100230666-A1 AMINE-TYPE POLYMERIC COMPOUND, AND LIGHT-EMITTING ELEMENT COMPRISING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-09-16 US disclosed
EP-2216356-A1 AMINE-TYPE POLYMERIC COMPOUND, AND LIGHT-EMITTING ELEMENT COMPRISING THE SAME Sumitomo Chemical Company, Limited (JP) 2010-08-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100230666-A1 AMINE-TYPE POLYMERIC COMPOUND, AND LIGHT-EMITTING ELEMENT COMPRISING THE SAME AHR, ARNT, MLLT1 NOX1 1335/4885GAA 3750/4885MAPT 2955/4885
US-20110309341-A1 AMINE POLYMER COMPOUND AND LIGHT EMITTING DEVICE USING THE SAME AHR, HRH3, HRH4 NOX1 1158/4885GAA 3715/4885MAPT 1067/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.