Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.37 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.37 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.37 |
| ▸ | ALB | P02768 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | RARB | P10826 | 1/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.37 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.37 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2107176 | 1.00 | PPARA (0.41) | PPARAPPARGALOX5PTGS1PTGS2 | |
| SCHEMBL2196410 | 0.83 | RIPK1 (0.37) | ALOX5LMNATSHRMEN1KMT2A | |
| SCHEMBL2195384 | 0.83 | RIPK1 (0.37) | ALOX5LMNATSHRMEN1KMT2A | |
| SCHEMBL2429212 | 0.81 | ESR1 (0.42) | ALOX5PTGS1LMNACYP2C9ESR1 | |
| SCHEMBL1448846 | 0.81 | ESR1 (0.42) | ALOX5PTGS1LMNACYP2C9ESR1 | |
| SCHEMBL1270470 | 0.80 | ALOX5 (0.51) | ALOX5LMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL2576026 | 0.80 | ALOX5 (0.51) | ALOX5LMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL2197076 | 0.80 | ALOX5 (0.51) | ALOX5LMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL2202724 | 0.79 | ALOX5 (0.43) | PPARAPPARGALOX5TSHRMEN1 | |
| SCHEMBL2198695 | 0.79 | MAPT (0.39) | ALOX5LMNACYP2C9KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110201589-A1 | NEW BRADYKININ B1 ANTAGONISTS | EVOTEC AG (DE) | 2011-08-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110201589-A1 | NEW BRADYKININ B1 ANTAGONISTS | BDKRB1, BDKRB2, BRS3 | PPARA 4286/4885PPARG 4780/4885ALOX5 2233/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.