Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 10/20 | 0.40 |
| ▸ | SMPD1 | P17405 | 5/20 | 0.40 |
| ▸ | GGPS1 | O95749 | 5/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6535584 | 0.94 | FDPS (0.38) | FDPSSMPD1 | |
| SCHEMBL1251054 | 0.85 | CYP4F2 (0.43) | — | |
| SCHEMBL28432671 | 0.83 | TDP1 (0.44) | — | |
| SCHEMBL150072 | 0.83 | FDPS (0.41) | FDPSSMPD1GGPS1 | |
| SCHEMBL17756699 | 0.82 | CYP4F2 (0.47) | FDPSSMPD1GGPS1 | |
| SCHEMBL30690424 | 0.81 | DGAT1 (0.35) | — | |
| SCHEMBL10706328 | 0.81 | SMPD1 (0.43) | FDPSSMPD1GGPS1 | |
| SCHEMBL29087510 | 0.81 | SMPD1 (0.43) | FDPSSMPD1GGPS1 | |
| Hydrochloric Acid SCHEMBL2418361 | 0.81 | FDPS (0.40) | FDPSSMPD1GGPS1 | |
| SCHEMBL25078774 | 0.81 | CYP4F2 (0.50) | FDPSSMPD1GGPS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8512971-B2 | Compounds and methods of use thereof for assaying lysophospholipase D activity | ECHELON BIOSCIENCES, INC. (US) | 2013-08-20 | — | — | US | disclosed |
| US-7989663-B2 | Compounds and methods of use thereof for assaying lysophospholipase D activity | ECHELON BIOSCIENCES INCORPORATED (US) | 2011-08-02 | — | — | US | disclosed |
| US-20100260682-A1 | Compounds and methods of use thereof for assaying lysophospholipase D activity | ECHELON BIOSCIENCES INCORPORATED (US) | 2010-10-14 | — | — | US | disclosed |
| US-20090068697-A1 | Compounds and methods of use thereof for assaying lysophospholipase D activity | ECHELON BIOSCIENCES INCORPORATED (US) | 2009-03-12 | — | — | US | disclosed |
| US-7459285-B2 | Compounds and methods of use thereof for assaying lysophospholipase D activity | ECHELON BIOSCIENCES INCORPORATED (US) | 2008-12-02 | — | — | US | disclosed |
| US-20040171096-A1 | Compounds and methods of use thereof for assaying lysophospholipase D activity | ECHELON BIOSCIENCES INCORPORATED | 2004-09-02 | — | — | US | disclosed |
| WO-2004053459-A2 | COMPOUNDS AND MEHTODS OF USE THEREOF FOR ASSAYING LYSOPHOSPHOLIPASE D ACTIVITY | ECHELON BIOSCIENCES INCORPORATED (US) | 2004-06-24 | — | — | WO | disclosed |
| CN-1142775-A | Preparation and use of immunoconjugates | IMMUNOMEDICS INC (US) | 1997-02-12 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090068697-A1 | Compounds and methods of use thereof for assaying lysophospholipase D activity | LYPLAL1, LPCAT3, LPCAT1 | FDPS 559/4885SMPD1 4/4885GGPS1 388/4885 |
| US-20100260682-A1 | Compounds and methods of use thereof for assaying lysophospholipase D activity | LYPLAL1, LPCAT3, LPCAT1 | FDPS 559/4885SMPD1 4/4885GGPS1 388/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.