SCHEMBL2239464

SCHEMBL2239464

c1csc(-c2cccc3snnc23)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.40
ALDH1A1 P00352 5/20 0.40
L3MBTL1 Q9Y468 3/20 0.40
MEN1 O00255 2/20 0.40
MAPT P10636 2/20 0.40
HPGD P15428 2/20 0.40
KMT2A Q03164 2/20 0.40
TDP1 Q9NUW8 1/20 0.40
ADRB1 P08588 1/20 0.39
LTK P29376 1/20 0.37
CDK5 Q00535 1/20 0.37
MST1R Q04912 1/20 0.37
DYRK1A Q13627 1/20 0.37
CLK4 Q9HAZ1 1/20 0.37
RAB9A P51151 4/20 0.37
NPC1 O15118 3/20 0.37
TDO2 P48775 1/20 0.37
SMN1; SMN2 Q16637 2/20 0.36
LTA4H P09960 2/20 0.36
HSD17B10 Q99714 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL428064 0.80 TDO2 (0.35) KDM4EALDH1A1L3MBTL1MEN1MAPT
SCHEMBL29387622 0.80 TDO2 (0.35) KDM4EALDH1A1L3MBTL1MEN1MAPT
SCHEMBL2127205 0.79 CYP2E1 (0.38) KDM4EALDH1A1L3MBTL1MEN1MAPT
SCHEMBL17538813 0.79 APP (0.32)
SCHEMBL1275013 0.77 TDO2 (0.38) KDM4EALDH1A1L3MBTL1MEN1MAPT
Fluorene SCHEMBL28732073 0.74 KDR (0.40) KDM4EALDH1A1L3MBTL1MEN1MAPT
SCHEMBL16714174 0.73 TDO2 (0.40) ALDH1A1L3MBTL1HPGDTDP1CLK4
Fluorene SCHEMBL28078910 0.72 MAOA (0.38) KDM4EALDH1A1MEN1MAPTHPGD
SCHEMBL18716826 0.71 RAB9A (0.36) KDM4EALDH1A1L3MBTL1MEN1MAPT
SCHEMBL18716824 0.71 NPC1 (0.36) KDM4EALDH1A1L3MBTL1MEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2536700-A2 SEMICONDUCTING POLYMERS Merck Patent GmbH (DE) 2012-12-26 EP claimed
WO-2012071641-A1 FUNCTIONALIZED SEMICONDUCTING POLYMERS FOR USE IN ORGANIC PHOTOVOLTAIC DEVICES NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2012-06-07 WO claimed
WO-2011098113-A2 SEMICONDUCTING POLYMERS MERCK PATENT GMBH (DE) 2011-08-18 WO claimed
US-11340362-B2 Direct conversion radiation detector Silverray Limited 2022-05-24 US disclosed
US-20190257959-A1 DIRECT CONVERSION RADIATION DETECTOR Silverray Limited (GB) 2019-08-22 US disclosed
EP-3060622-A1 CONJUGATED POLYMERS Merck Patent GmbH (DE) 2016-08-31 EP disclosed
WO-2015058827-A1 CONJUGATED POLYMERS MERCK PATENT GMBH (DE) 2015-04-30 WO disclosed
US-20140187716-A1 PROCESS FOR THE SYNTHESIS OF CONJUGATED POLYMERS THE UNIVERSITY OF MELBOURNE (AU) 2014-07-03 US disclosed
EP-2731974-A1 PROCESS FOR THE SYNTHESIS OF CONJUGATED POLYMERS The University of Melbourne (AU) 2014-05-21 EP disclosed
CN-102504803-B Organic luminescent material solution for improving uniformity of inkjet printing films by convection and preparation method thereof CHANGCHUN APPLIED CHEMISTRY 2013-11-27 CN disclosed
WO-2013010209-A1 PROCESS FOR THE SYNTHESIS OF CONJUGATED POLYMERS THE UNIVERSITY OF MELBOURNE (AU) 2013-01-24 WO disclosed
CN-102504804-A Organic luminescent material solution for improving uniformity of ink-jet printing thin film by inhibiting edge flowing and preparation method thereof CHANGCHUN APPLIED CHEMISTRY 2012-06-20 CN disclosed
CN-102504804-A Organic luminescent material solution for improving uniformity of ink-jet printing thin film by inhibiting edge flowing and preparation method thereof CHANGCHUN APPLIED CHEMISTRY 2012-06-20 CN disclosed
CN-102504803-A Organic luminescent material solution for improving uniformity of inkjet printing films by convection and preparation method thereof CHANGCHUN APPLIED CHEMISTRY 2012-06-20 CN disclosed