SCHEMBL22394792

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5695788	0.82	CTNNB1 (0.67)	CTNNB1WNT3AATMRAB9ANPC1
	SCHEMBL22394673	0.80	SMN1; SMN2 (0.61)	CTNNB1WNT3AATMRAB9ANPC1
	SCHEMBL22394706	0.78	CTNNB1 (0.67)	CTNNB1WNT3AATMRAB9ANPC1
	SCHEMBL6794489	0.77	NPC1 (0.59)	CTNNB1WNT3AATMRAB9ANPC1
	SCHEMBL8967686	0.75	KMT2A (0.42)	RAB9ANPC1SMN1; SMN2HPGDPKM
	SCHEMBL12688363	0.75	RAB9A (0.49)	CTNNB1WNT3AATMRAB9ANPC1
	SCHEMBL10027736	0.74	CTNNB1 (1.00)	CTNNB1WNT3AATMRAB9ANPC1
	SCHEMBL15968604	0.73	CTNNB1 (1.00)	CTNNB1WNT3AATMHPGDPKM
	SCHEMBL1092875	0.73	ATM (1.00)	CTNNB1WNT3AATMRAB9ANPC1
	SCHEMBL653025	0.72	PKM (0.87)	CTNNB1WNT3AATMHPGDPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.