Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | PNMT | P11086 | 1/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8796327 | 1.00 | TAAR1 (0.38) | TAAR1DPP4MTNR1AMTNR1BPNMT | |
| SCHEMBL15057877 | 0.85 | MTNR1A (0.38) | MTNR1AMTNR1BCYP1A2LMNAKDM4E | |
| SCHEMBL12301968 | 0.84 | ADRA2A (0.47) | MTNR1AMTNR1BIRAK4KDM4E | |
| SCHEMBL7013166 | 0.84 | MCHR1 (0.46) | TAAR1DPP4MTNR1AMTNR1BPNMT | |
| SCHEMBL10056778 | 0.83 | TAAR1 (0.45) | TAAR1 | |
| SCHEMBL74606 | 0.83 | TAAR1 (0.45) | TAAR1 | |
| SCHEMBL73995 | 0.83 | TAAR1 (0.45) | TAAR1 | |
| SCHEMBL14092183 | 0.83 | ALOX15 (0.35) | TAAR1MTNR1AMTNR1BIRAK4CYP1A2 | |
| SCHEMBL11303009 | 0.82 | MTNR1A (0.47) | MTNR1AMTNR1BIRAK4CYP1A2LMNA | |
| SCHEMBL855754 | 0.81 | IRAK4 (0.47) | TAAR1PNMTIRAK4SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3704118-A1 | AMINOIMIDAZOPYRIDAZINES AS KINASE INHIBITORS | Bristol-Myers Squibb Company (US) | 2020-09-09 | — | — | EP | disclosed |