SCHEMBL2240115

SCHEMBL2240115

N=C(N)NCCC[C@H](NC(=O)CN)C(=O)Nc1ccc([N+](=O)[O-])cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PDF Q9HBH1 1/20 0.50
▸ SSTR3 P32745 1/20 0.43
▸ ALDH1A1 P00352 5/20 0.41
▸ SMN1; SMN2 Q16637 5/20 0.41
▸ MAPT P10636 5/20 0.41
▸ LMNA P02545 3/20 0.41
▸ HTT P42858 3/20 0.41
▸ KMT2A Q03164 6/20 0.40
▸ MEN1 O00255 5/20 0.40
▸ GLA P06280 3/20 0.40
▸ NPSR1 Q6W5P4 1/20 0.39
▸ NPY1R P25929 1/20 0.39
▸ NPY2R P49146 1/20 0.39
▸ NPY4R P50391 1/20 0.39
▸ NPY5R Q15761 1/20 0.39
▸ POLB P06746 3/20 0.39
▸ CA12 O43570 1/20 0.39
▸ CA1 P00915 1/20 0.39
▸ CA2 P00918 1/20 0.39
▸ CA4 P22748 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7356173 0.99 PDF (0.49) PDFSSTR3ALDH1A1SMN1; SMN2MAPT
SCHEMBL29378049 0.88 PDF (0.51) PDFSSTR3ALDH1A1SMN1; SMN2MAPT
SCHEMBL2567001 0.88 PDF (0.48) PDFSSTR3ALDH1A1SMN1; SMN2MAPT
SCHEMBL8723156 0.88 PDF (0.52) PDFSSTR3ALDH1A1SMN1; SMN2MAPT
SCHEMBL16446037 0.88 PDF (0.50) PDFSSTR3ALDH1A1SMN1; SMN2MAPT
SCHEMBL15286730 0.87 PDF (0.44) PDFSSTR3ALDH1A1SMN1; SMN2MAPT
SCHEMBL5582797 0.87 PDF (0.44) PDFSSTR3ALDH1A1SMN1; SMN2MAPT
Hydrochloric Acid SCHEMBL4449414 0.86 PDF (0.44) PDFSSTR3ALDH1A1SMN1; SMN2MAPT
SCHEMBL1780776 0.86 PDF (0.46) PDFSSTR3ALDH1A1SMN1; SMN2MAPT
SCHEMBL10943828 0.86 PDF (0.46) PDFSSTR3ALDH1A1SMN1; SMN2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260071253-A1 METHOD FOR DETECTING THE PRESENCE, IDENTIFICATION AND QUANTIFICATION IN A BLOOD SAMPLE OF ANTICOAGULANTS WHICH ARE BLOOD COAGULATION ENZYMES INHIBITORS, AND MEANS FOR THE IMPLEMENTATION THEREOF STAGO DIAGNOSTICA (FR) 2026-03-12 — — US claimed
US-12473584-B2 Method for detecting the presence, identification and quantification in a blood sample of anticoagulants which are blood coagulation enzymes inhibitors, and means for the implementation thereof DIAGNOSTICA STAGO (FR) 2025-11-18 — — US claimed
EP-3891752-B1 METHOD FOR DETECTING THE PRESENCE, IDENTIFICATION AND QUANTIFICATION IN A BLOOD SAMPLE OF ANTICOAGULANTS WHICH ARE INHIBITORS OF BLOOD COAGULATION ENZYMES, AND MEANS FOR THE IMPLEMENTATION THEREOF STAGO DIAGNOSTICA (FR) 2025-08-13 — — EP claimed
US-20240353431-A1 SELECTIVE MEASUREMENT OF HUMAN FACTOR VIII TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2024-10-24 — — US claimed
EP-4388124-A1 SELECTIVE MEASUREMENT OF HUMAN FACTOR VIII Takeda Pharmaceutical Company Limited (JP) 2024-06-26 — — EP claimed
CN-117836425-A Selective measurement of human factor VIII 武田药品工业株式会社 2024-04-05 — — CN claimed
WO-2023021311-A1 SELECTIVE MEASUREMENT OF HUMAN FACTOR VIII TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2023-02-23 — — WO claimed
US-20220380833-A1 Universal Calibration Method for Assaying Enzymatic Inhibitors DIAGNOSTICA STAGO (FR) 2022-12-01 — — US claimed
EP-0476715-B1 Method and composition for the determination of chloride ions in fluids UNIV SOUTHERN AUSTRALIA (AU) 1996-12-18 — — EP claimed
US-5409814-A Quantitative analysis using enzymes BOEHRINGER MANNHEIM GMBH (DE) 1995-04-25 — — US claimed
EP-0476715-A2 Method and composition for the determination of chloride ions in fluids THE FLINDERS UNIVERSITY OF SOUTH AUSTRALIA (AU) 1992-03-25 — — EP claimed
US-20260071253-A1 METHOD FOR DETECTING THE PRESENCE, IDENTIFICATION AND QUANTIFICATION IN A BLOOD SAMPLE OF ANTICOAGULANTS WHICH ARE BLOOD COAGULATION ENZYMES INHIBITORS, AND MEANS FOR THE IMPLEMENTATION THEREOF STAGO DIAGNOSTICA (FR) 2026-03-12 — — US disclosed
US-20260014236-A1 ACTIVATORS OF COAGULATION FACTOR X AND FORMULATIONS THEREOF FOR TREATING BLEEDING DISORDERS JIANGSU BIOJETAY BIOTECHNOLOGY CO., LTD. (CN) 2026-01-15 — — US disclosed
US-20250389737-A1 FACTOR Xa REAGENT INSTR LABORATORY CO (US) 2025-12-25 — — US disclosed
EP-4667582-A1 FACTOR XA REAGENT Instrumentation Laboratory Company (US) 2025-12-24 — — EP disclosed
EP-0476715-A2 Method and composition for the determination of chloride ions in fluids THE FLINDERS UNIVERSITY OF SOUTH AUSTRALIA (AU) 1992-03-25 — — EP disclosed
EP-0471391-A2 Determination of ions in fluids THE FLINDERS UNIVERSITY OF SOUTH AUSTRALIA (AU) 1992-02-19 — — EP disclosed
EP-0309525-A1 DETERMINATION OF IONS IN FLUIDS THE FLINDERS UNIVERSITY OF SOUTH AUSTRALIA (AU) 1989-04-05 — — EP disclosed
WO-1988008137-A1 DETERMINATION OF IONS IN FLUIDS THE FLINDERS UNIVERSITY OF SOUTH AUSTRALIA (AU) 1988-10-20 — — WO disclosed
EP-0286039-A2 Determination of potassium ions in fluids THE FLINDERS UNIVERSITY OF SOUTH AUSTRALIA (AU) 1988-10-12 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260071253-A1 METHOD FOR DETECTING THE PRESENCE, IDENTIFICATION AND QUANTIFICATION IN A BLOOD SAMPLE OF ANTICOAGULANTS WHICH ARE BLOOD COAGULATION ENZYMES INHIBITORS, AND MEANS FOR THE IMPLEMENTATION THEREOF TFPI, F13B, TFPI2 PDF 4130/4885SSTR3 4809/4885ALDH1A1 1662/4885
US-20250389737-A1 FACTOR Xa REAGENT F9, F11, TFPI PDF 1696/4885SSTR3 4536/4885ALDH1A1 3524/4885
US-20260014236-A1 ACTIVATORS OF COAGULATION FACTOR X AND FORMULATIONS THEREOF FOR TREATING BLEEDING DISORDERS F8, F5, F12 PDF 840/4885SSTR3 2459/4885ALDH1A1 4656/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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