Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA7 | P43166 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | USP2 | O75604 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | SCN1A | P35498 | 1/20 | 0.51 |
| ▸ | HTR2B | P41595 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22401399 | 0.82 | KDM4E (0.48) | ALDH1A1KDM4EHRH3KMT2AMEN1 | |
| SCHEMBL13930969 | 0.78 | ALDH1A1 (0.62) | SMN1; SMN2GAAALDH1A1KDM4ECA12 | |
| SCHEMBL13952296 | 0.78 | HRH3 (0.67) | ALDH1A1MAPK1CYP1A2CHRM2CHRM1 | |
| SCHEMBL5300447 | 0.77 | ALDH1A1 (0.64) | SMN1; SMN2GAAALDH1A1KDM4ECA12 | |
| SCHEMBL21049830 | 0.77 | ALDH1A1 (0.63) | SMN1; SMN2GAAALDH1A1KDM4ECA12 | |
| SCHEMBL9505607 | 0.77 | ALDH1A1 (0.64) | SMN1; SMN2GAAALDH1A1KDM4ECA12 | |
| SCHEMBL1395845 | 0.77 | LTA4H (0.61) | SMN1; SMN2GAAALDH1A1KDM4ECA12 | |
| SCHEMBL3007594 | 0.76 | GAA (0.71) | SMN1; SMN2GAAALDH1A1KDM4ECA12 | |
| SCHEMBL4404318 | 0.76 | KDM4E (0.75) | SMN1; SMN2GAAALDH1A1KDM4ECA12 | |
| Hydrochloric Acid SCHEMBL14742324 | 0.75 | GAA (0.70) | SMN1; SMN2GAAALDH1A1KDM4ECA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3707125-A1 | CAFFEIC ACID DERIVATIVES FOR TREATING HYPERPROLIFERATIVE DISEASES | Board Of Regents, The University Of Texas System (US) | 2020-09-16 | — | — | EP | disclosed |