Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.64 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | USP2 | O75604 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.57 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.57 |
| ▸ | HTR2A | P28223 | 1/20 | 0.57 |
| ▸ | SCN1A | P35498 | 1/20 | 0.57 |
| ▸ | HTR2B | P41595 | 1/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.57 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.57 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.57 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.57 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7333720 | 0.80 | KMT2A (0.59) | ALDH1A1LMNAUSP2SMN1; SMN2TSHR | |
| SCHEMBL7333709 | 0.80 | KMT2A (0.59) | ALDH1A1LMNAUSP2SMN1; SMN2TSHR | |
| SCHEMBL29508217 | 0.80 | ALDH1A1 (0.88) | ALDH1A1LMNAUSP2SMN1; SMN2TSHR | |
| SCHEMBL21049830 | 0.77 | ALDH1A1 (0.63) | ALDH1A1LMNAUSP2SMN1; SMN2TSHR | |
| SCHEMBL5300447 | 0.77 | ALDH1A1 (0.64) | ALDH1A1LMNAUSP2SMN1; SMN2TSHR | |
| SCHEMBL22401398 | 0.77 | SMN1; SMN2 (0.59) | ALDH1A1LMNAUSP2SMN1; SMN2TSHR | |
| SCHEMBL4404318 | 0.76 | KDM4E (0.75) | ALDH1A1LMNAUSP2SMN1; SMN2MAPK1 | |
| SCHEMBL7331713 | 0.76 | ALDH1A1 (0.56) | ALDH1A1LMNAUSP2SMN1; SMN2TSHR | |
| SCHEMBL13930969 | 0.75 | ALDH1A1 (0.62) | ALDH1A1LMNAUSP2SMN1; SMN2TSHR | |
| SCHEMBL13952296 | 0.75 | HRH3 (0.67) | ALDH1A1MAPK1CYP1A2CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0552309-A1 | NEW PROCESS FOR BIOPHOSPHORYLATING ORGANIC COMPOUNDS | MERCK & CO. INC. (US) | 1993-07-28 | — | — | EP | disclosed |
| WO-1992006992-A2 | NEW PROCESS FOR BIOPHOSPHORYLATING ORGANIC COMPOUNDS | MERCK & CO., INC. (US) | 1992-04-30 | — | — | WO | disclosed |