Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAE1 | Q13564 | 7/20 | 0.36 |
| ▸ | UBA3 | Q8TBC4 | 7/20 | 0.36 |
| ▸ | TYMP | P19971 | 1/20 | 0.36 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.35 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 5/20 | 0.35 |
| ▸ | HTR7 | P34969 | 5/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23456069 | 1.00 | NAE1 (0.36) | NAE1UBA3TYMPSLC6A1SLC6A11 | |
| SCHEMBL23455989 | 0.87 | NAE1 (0.40) | NAE1UBA3TYMPSLC6A1SLC6A11 | |
| SCHEMBL23456083 | 0.85 | SLC6A1 (0.33) | TYMPSLC6A1SLC6A11HTR1AHTR7 | |
| SCHEMBL23455982 | 0.84 | HTR1A (0.33) | TYMPSLC6A1SLC6A11HTR1AHTR7 | |
| SCHEMBL23455980 | 0.83 | SLC6A11 (0.35) | NAE1UBA3TYMPSLC6A1SLC6A11 | |
| SCHEMBL30960669 | 0.77 | EGFR (0.48) | NAE1UBA3 | |
| SCHEMBL23456613 | 0.77 | EGFR (0.48) | NAE1UBA3 | |
| SCHEMBL23456175 | 0.73 | TYMP (0.37) | NAE1UBA3TYMPSLC6A1SLC6A11 | |
| SCHEMBL23456248 | 0.73 | TYMP (0.37) | NAE1UBA3TYMPSLC6A1SLC6A11 | |
| SCHEMBL23456067 | 0.73 | ACP1 (0.39) | NAE1UBA3TYMPSLC6A1SLC6A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3707151-A1 | STING MODULATOR COMPOUNDS, AND METHODS OF MAKING AND USING | Takeda Pharmaceutical Company Limited (JP) | 2020-09-16 | — | — | EP | disclosed |