Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 7/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MLNR | O43193 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22402016 | 0.96 | PDK2 (0.37) | PDK2TDP1ALDH1A1KDM4ECYP1A2 | |
| SCHEMBL20806572 | 0.92 | PDK2 (0.33) | PDK2TDP1ALDH1A1KDM4ECYP1A2 | |
| SCHEMBL20806442 | 0.91 | PDK2 (0.36) | PDK2TDP1ALDH1A1KDM4ECYP1A2 | |
| SCHEMBL13907762 | 0.91 | PDK2 (0.39) | PDK2TDP1ALDH1A1KDM4ECYP1A2 | |
| SCHEMBL22401978 | 0.91 | PDK2 (0.33) | PDK2TDP1ALDH1A1KDM4ECYP1A2 | |
| SCHEMBL24877060 | 0.90 | ALDH1A1 (0.34) | PDK2TDP1ALDH1A1KDM4ECYP1A2 | |
| SCHEMBL20806549 | 0.90 | PDK2 (0.38) | PDK2TDP1ALDH1A1KDM4ECYP1A2 | |
| SCHEMBL22058453 | 0.90 | PDK2 (0.40) | PDK2TDP1ALDH1A1KDM4ECYP1A2 | |
| SCHEMBL26603180 | 0.90 | PDK2 (0.35) | PDK2TDP1ALDH1A1MLNRNR1I2 | |
| SCHEMBL23587750 | 0.89 | PDK2 (0.33) | PDK2TDP1ALDH1A1KDM4ECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200283386-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2020-09-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200283386-A1 | MATERIALS FOR ELECTRONIC DEVICES | EFNA1, GPX1, SOD1 | PDK2 461/4885TDP1 1748/4885ALDH1A1 312/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.