Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | GLA | P06280 | 1/20 | 0.58 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.56 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.52 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.52 |
| ▸ | NOS2 | P35228 | 1/20 | 0.51 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.51 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.51 |
| ▸ | FOS | P01100 | 1/20 | 0.50 |
| ▸ | TTR | P02766 | 1/20 | 0.50 |
| ▸ | JUN | P05412 | 1/20 | 0.50 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.50 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.50 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.50 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12349734 | 0.91 | TAAR1 (0.56) | TAAR1TSHRMAPK1LMNAGLA | |
| SCHEMBL13616947 | 0.86 | TAAR1 (0.51) | TAAR1TSHRMAPK1LMNAGLA | |
| SCHEMBL12349742 | 0.84 | ALOX5 (0.57) | ALOX5GAA | |
| SCHEMBL12349730 | 0.84 | MTNR1A (0.49) | TAAR1TSHRMAPK1LMNAGLA | |
| SCHEMBL13492499 | 0.82 | TAAR1 (0.56) | TAAR1TSHRMAPK1LMNAGLA | |
| SCHEMBL12349745 | 0.80 | ALOX5 (0.56) | ALOX5GAA | |
| SCHEMBL13616943 | 0.80 | MTNR1A (0.46) | TAAR1TSHRMAPK1LMNAGLA | |
| SCHEMBL26548300 | 0.80 | TAAR1 (0.38) | TAAR1TSHRMAPK1LMNAGLA | |
| SCHEMBL29604390 | 0.80 | PTPN1 (0.82) | TAAR1TSHRMAPK1LMNAGLA | |
| SCHEMBL17780116 | 0.80 | PTPN1 (0.82) | TAAR1TSHRMAPK1LMNAGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200281836-A1 | COSMETIC | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2020-09-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200281836-A1 | COSMETIC | CUTA, H1-0, H1-10 | TAAR1 657/4885TSHR 2279/4885MAPK1 4061/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.