Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 5/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.31 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.31 |
| ▸ | CDK4 | P11802 | 1/20 | 0.31 |
| ▸ | CCND1 | P24385 | 1/20 | 0.31 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | TNFRSF1A | P19438 | 3/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.30 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.30 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22402552 | 0.87 | PDK2 (0.32) | PDK2PGR | |
| SCHEMBL22402526 | 0.85 | PDK2 (0.37) | ERN1PDK2 | |
| SCHEMBL22402558 | 0.84 | — | — | |
| SCHEMBL5266013 | 0.80 | PDK2 (0.51) | ERN1PDK2PGRSLC6A11HDAC3 | |
| SCHEMBL22402542 | 0.79 | PDK2 (0.32) | PDK2 | |
| SCHEMBL18812931 | 0.76 | PDK2 (0.56) | ERN1PDK2PGRSLC6A11HDAC3 | |
| SCHEMBL22402520 | 0.76 | PDK2 (0.37) | PDK2PGR | |
| SCHEMBL22402563 | 0.75 | PDK2 (0.36) | PDK2PGR | |
| SCHEMBL31111276 | 0.74 | ERN1 (0.41) | ERN1 | |
| SCHEMBL22402557 | 0.73 | PDK2 (0.31) | PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230039657-A1 | DETECTION METHOD | UNIV QUEENSLAND (AU) | 2023-02-09 | — | — | US | disclosed |
| US-20200284728-A1 | DETECTION METHOD | THE UNIVERSITY OF QUEENSLAND (AU) | 2020-09-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230039657-A1 | DETECTION METHOD | OPRK1, OPRM1, SIGMAR1 | ERN1 1556/4885PDK2 3509/4885PGR 1627/4885 |
| US-20200284728-A1 | DETECTION METHOD | OPRK1, OPRM1, SIGMAR1 | ERN1 1556/4885PDK2 3509/4885PGR 1627/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.