Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 2/20 | 0.46 |
| ▸ | SRC | P12931 | 2/20 | 0.46 |
| ▸ | KDR | P35968 | 2/20 | 0.46 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.46 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | FYN | P06241 | 1/20 | 0.46 |
| ▸ | YES1 | P07947 | 1/20 | 0.46 |
| ▸ | LYN | P07948 | 1/20 | 0.46 |
| ▸ | HCK | P08631 | 1/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.46 |
| ▸ | FGR | P09769 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.46 |
| ▸ | PRKACA | P17612 | 1/20 | 0.46 |
| ▸ | EPHB2 | P29323 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22530133 | 0.81 | IDO1 (0.38) | LCKSRCKDRRIPK2ABL1 | |
| SCHEMBL22403092 | 0.81 | HPGD (0.46) | SRCABL1CYP1A2MAPK14SMN1; SMN2 | |
| SCHEMBL26542947 | 0.77 | KDM4E (0.45) | SMN1; SMN2KDM4EEGLN2ALDH1A1LMNA | |
| SCHEMBL22530233 | 0.76 | HCAR3 (0.43) | SMN1; SMN2KDM4EALDH1A1HTTPOLB | |
| SCHEMBL3923342 | 0.71 | GRIN2B (0.31) | — | |
| SCHEMBL4483738 | 0.70 | DRD1 (0.47) | LCKSRCKDRDAPK3RIPK2 | |
| SCHEMBL28265876 | 0.69 | LCK (0.41) | LCKSRCKDRDAPK3RIPK2 | |
| SCHEMBL21720017 | 0.69 | DAPK3 (0.33) | LCKSRCKDRDAPK3RIPK2 | |
| SCHEMBL31617446 | 0.66 | RIPK2 (0.48) | LCKSRCKDRDAPK3RIPK2 | |
| SCHEMBL11281776 | 0.66 | ALDH1A1 (0.53) | SRCSMN1; SMN2KDM4EALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11786575-B2 | Endoparasitic depsipeptides | ZOETIS SERVICES LLC (US) | 2023-10-17 | — | — | US | disclosed |
| US-20220211802-A1 | Endoparasitic Depsipeptides | ZOETIS SERVICES LLC | 2022-07-07 | — | — | US | disclosed |
| US-11331369-B2 | Endoparasitic depsipeptides | ZOETIS SERVICES LLC (US) | 2022-05-17 | — | — | US | disclosed |
| US-20200282016-A1 | Endoparasitic Depsipeptides | ZOETIS SERVICES LLC | 2020-09-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11786575-B2 | Endoparasitic depsipeptides | VIP, PREP, NGLY1 | LCK 4796/4885SRC 4758/4885KDR 4521/4885 |
| US-20200282016-A1 | Endoparasitic Depsipeptides | VIP, PREP, NGLY1 | LCK 4796/4885SRC 4758/4885KDR 4521/4885 |
| US-20220211802-A1 | Endoparasitic Depsipeptides | VIP, PREP, NGLY1 | LCK 4796/4885SRC 4758/4885KDR 4521/4885 |
| US-11331369-B2 | Endoparasitic depsipeptides | VIP, PREP, NGLY1 | LCK 4796/4885SRC 4758/4885KDR 4521/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.