Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15730580 | 0.77 | L3MBTL1 (0.33) | PARP1L3MBTL1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL15723691 | 0.76 | L3MBTL1 (0.34) | L3MBTL1KDM4EALDH1A1HSD17B10CASP1 | |
| SCHEMBL23937891 | 0.73 | KDM4E (0.33) | L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL20631154 | 0.72 | KDM4E (0.35) | L3MBTL1KDM4EALDH1A1HSD17B10CASP1 | |
| SCHEMBL23937924 | 0.69 | KDM5A (0.33) | KDM4EALDH1A1HSD17B10CASP1CASP7 | |
| SCHEMBL17616501 | 0.69 | PARP1 (0.33) | PARP1 | |
| SCHEMBL22402968 | 0.69 | PARP1 (0.37) | PARP1L3MBTL1KDM4EALDH1A1MAPK1 | |
| SCHEMBL17616497 | 0.67 | LMNA (0.49) | KDM4EALDH1A1HSD17B10 | |
| SCHEMBL24997633 | 0.66 | PARP1 (0.31) | PARP1 | |
| SCHEMBL17616487 | 0.64 | PARP1 (0.31) | PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11786575-B2 | Endoparasitic depsipeptides | ZOETIS SERVICES LLC (US) | 2023-10-17 | — | — | US | disclosed |
| US-20220211802-A1 | Endoparasitic Depsipeptides | ZOETIS SERVICES LLC | 2022-07-07 | — | — | US | disclosed |
| US-11331369-B2 | Endoparasitic depsipeptides | ZOETIS SERVICES LLC (US) | 2022-05-17 | — | — | US | disclosed |
| US-20200282016-A1 | Endoparasitic Depsipeptides | ZOETIS SERVICES LLC | 2020-09-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11786575-B2 | Endoparasitic depsipeptides | VIP, PREP, NGLY1 | PARP1 1285/4885L3MBTL1 445/4885KDM4E 3941/4885 |
| US-20200282016-A1 | Endoparasitic Depsipeptides | VIP, PREP, NGLY1 | PARP1 1285/4885L3MBTL1 445/4885KDM4E 3941/4885 |
| US-20220211802-A1 | Endoparasitic Depsipeptides | VIP, PREP, NGLY1 | PARP1 1285/4885L3MBTL1 445/4885KDM4E 3941/4885 |
| US-11331369-B2 | Endoparasitic depsipeptides | VIP, PREP, NGLY1 | PARP1 1285/4885L3MBTL1 445/4885KDM4E 3941/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.