SCHEMBL22403986

SCHEMBL22403986

Cc1c(-c2ccccc2)n(-c2ccc(-n3c4ccccc4c4ccccc43)cc2)c2ccc3c(c(C)c(-c4ccccc4)n3-c3ccc(-n4c5ccccc5c5ccccc54)cc3)c12

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.52
KDM4E B2RXH2 2/20 0.52
ATM Q13315 1/20 0.52
IL1R1 P14778 1/20 0.47
KMT2A Q03164 4/20 0.46
ALDH1A1 P00352 3/20 0.46
MEN1 O00255 2/20 0.46
HTT P42858 2/20 0.46
MAPT P10636 1/20 0.46
ESR1 P03372 1/20 0.37
ESR2 Q92731 1/20 0.37
CYP2C19 P33261 2/20 0.37
CYP1A2 P05177 1/20 0.37
CYP2C9 P11712 1/20 0.37
RECQL P46063 1/20 0.37
HDAC4 P56524 1/20 0.36
MAPK1 P28482 1/20 0.36
LMNA P02545 2/20 0.36
HSD17B10 Q99714 2/20 0.35
PTPN1 P18031 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11986680 0.85 L3MBTL1 (0.49) L3MBTL1KDM4EATMIL1R1KMT2A
SCHEMBL11986678 0.80 L3MBTL1 (0.47) L3MBTL1KDM4EATMIL1R1KMT2A
SCHEMBL22403988 0.79 KDM4E (0.45) L3MBTL1KDM4EATMIL1R1KMT2A
SCHEMBL11986682 0.78 L3MBTL1 (0.41) L3MBTL1KDM4EATMIL1R1KMT2A
SCHEMBL17019460 0.78 L3MBTL1 (0.61) L3MBTL1KDM4EATMIL1R1KMT2A
SCHEMBL15780987 0.78 L3MBTL1 (0.61) L3MBTL1KDM4EATMIL1R1KMT2A
SCHEMBL4883027 0.78 IL1R1 (0.47) L3MBTL1KDM4EATMIL1R1KMT2A
SCHEMBL18494573 0.77 KDM4E (0.46) L3MBTL1KDM4EATMIL1R1KMT2A
SCHEMBL18124857 0.76 L3MBTL1 (0.57) L3MBTL1KDM4EATMIL1R1KMT2A
SCHEMBL30022478 0.76 L3MBTL1 (0.57) L3MBTL1KDM4EATMIL1R1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11780846-B2 Compound, organic electroluminescent device including the same and electronic apparatus WUHAN TIANMA MICRO-ELECTRONICS CO., LTD. (CN) 2023-10-10 US disclosed
US-11780846-B2 Compound, organic electroluminescent device including the same and electronic apparatus WUHAN TIANMA MICRO-ELECTRONICS CO., LTD. (CN) 2023-10-10 US disclosed
US-20200283448-A1 COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE INCLUDING THE SAME AND ELECTRONIC APPARATUS WUHAN TIANMA MICRO-ELECTRONICS CO., LTD. (CN) 2020-09-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200283448-A1 COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE INCLUDING THE SAME AND ELECTRONIC APPARATUS GJB2, SLC7A5, GJA1 L3MBTL1 541/4885KDM4E 2146/4885ATM 2235/4885
US-11780846-B2 Compound, organic electroluminescent device including the same and electronic apparatus GJB2, SLC7A5, GJA1 L3MBTL1 541/4885KDM4E 2146/4885ATM 2235/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.