Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.45 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.45 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29031806 | 0.86 | PTGS2 (0.59) | EPHX1PTGS2LMNASMN1; SMN2APP | |
| SCHEMBL3671835 | 0.85 | PTGS2 (0.68) | PTGS2SLC1A3SLC1A2SLC1A1MCL1 | |
| SCHEMBL28775715 | 0.82 | SCN9A (0.48) | EPHX1PTGS2DPP4DPP7APP | |
| SCHEMBL2357849 | 0.82 | NPSR1 (0.54) | EPHX1PTGS2LMNASMN1; SMN2NPSR1 | |
| SCHEMBL8696877 | 0.80 | PTGS2 (0.71) | EPHX1PTGS2SMN1; SMN2 | |
| SCHEMBL7019484 | 0.78 | F10 (0.47) | EPHX1CA12CA1CA2CA9 | |
| SCHEMBL23198148 | 0.77 | CA12 (0.46) | CA12CA1CA2CA9PTGS2 | |
| SCHEMBL29225757 | 0.77 | CA12 (0.50) | CA12CA1CA2CA9SLC1A3 | |
| SCHEMBL23198147 | 0.77 | CA12 (0.46) | CA12CA1CA2CA9PTGS2 | |
| SCHEMBL30057689 | 0.77 | SLC1A3 (0.55) | CA12CA1CA2CA9PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200281892-A1 | ORAL FORMULATIONS OF PYRROLIDINE DERIVATIVES | ReproNovo SA (CH) | 2020-09-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200281892-A1 | ORAL FORMULATIONS OF PYRROLIDINE DERIVATIVES | KDM5A, KDM5C, KDM5B | EPHX1 1063/4885CA12 4764/4885CA1 4566/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.