Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 14/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | PLG | P00747 | 1/20 | 0.42 |
| ▸ | PROC | P04070 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7027094 | 0.86 | F10 (0.45) | F10CA12CA1CA2CA9 | |
| SCHEMBL7025525 | 0.82 | F10 (0.44) | F10PRSS1SCN9AF2 | |
| SCHEMBL7027056 | 0.82 | F10 (0.49) | F10CA12CA1CA2CA9 | |
| SCHEMBL7024688 | 0.82 | F10 (0.43) | F10PRSS1SCN9AF2 | |
| SCHEMBL29031806 | 0.81 | PTGS2 (0.59) | EPHX1PTGS2 | |
| SCHEMBL8350056 | 0.79 | CA1 (0.54) | CA12CA1CA2CA9PTGS2 | |
| SCHEMBL22404548 | 0.78 | EPHX1 (0.47) | CA12CA1CA2CA9EPHX1 | |
| SCHEMBL7027498 | 0.78 | MMP3 (0.47) | F10CA1CA2PRSS1SCN9A | |
| SCHEMBL28775715 | 0.77 | SCN9A (0.48) | EPHX1PTGS2SCN9A | |
| SCHEMBL2357849 | 0.77 | NPSR1 (0.54) | EPHX1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1309549-A1 | ACETAMIDE DERIVATIVES AND THE USE THEREOF AS INHIBITORS OF COAGULATION FACTORS XA AND VIIA | MERCK PATENT GmbH (DE) | 2003-05-14 | — | — | EP | disclosed |
| WO-2002010127-A1 | ACETAMIDE DERIVATIVES AND THE USE THEREOF AS INHIBITORS OF COAGULATION FACTORS XA AND VIIA | MERCK PATENT GMBH (DE) | 2002-02-07 | — | — | WO | disclosed |