SCHEMBL224048

SCHEMBL224048

CC(C)(C)c1cc(S)cc(C(C)(C)C)c1O

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 4/20 0.64
CA1 P00915 2/20 0.64
ALDH1A1 P00352 7/20 0.61
SMN1; SMN2 Q16637 5/20 0.61
POLB P06746 1/20 0.61
TYR P14679 1/20 0.61
ALOX15 P16050 4/20 0.54
MAPT P10636 4/20 0.54
HPN P05981 1/20 0.54
SIRT5 Q9NXA8 1/20 0.54
GAA P10253 4/20 0.48
MEN1 O00255 4/20 0.48
KMT2A Q03164 4/20 0.48
TSHR P16473 4/20 0.48
NPSR1 Q6W5P4 4/20 0.48
LMNA P02545 3/20 0.48
HTT P42858 2/20 0.48
GALR3 O60755 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
CYP1A2 P05177 5/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17309883 0.88 CA2 (0.50) CA2CA1ALDH1A1SMN1; SMN2POLB
SCHEMBL891539 0.86 CYP2C9 (0.63) CA2CA1ALDH1A1SMN1; SMN2POLB
SCHEMBL31196962 0.86 CYP2C9 (0.63) CA2CA1ALDH1A1SMN1; SMN2POLB
Toluene SCHEMBL27737615 0.84 CA2 (0.55) CA2CA1ALDH1A1SMN1; SMN2POLB
SCHEMBL10506187 0.84 CA2 (0.47) CA2CA1ALDH1A1SMN1; SMN2POLB
SCHEMBL21241548 0.82 CA2 (0.45) CA2CA1ALDH1A1SMN1; SMN2POLB
SCHEMBL31196955 0.81 HSPA5 (0.53) CA2CA1ALDH1A1SMN1; SMN2POLB
SCHEMBL31196986 0.81 CA2 (0.43) CA2CA1ALDH1A1SMN1; SMN2POLB
SCHEMBL21241382 0.80 CA2 (0.42) CA2CA1ALDH1A1SMN1; SMN2POLB
SCHEMBL803157 0.78 CA2 (1.00) CA2CA1ALDH1A1SMN1; SMN2POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 630 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120072396-A Cable for new energy vehicle direct current charging system 玖开特种线缆(上海)有限公司 2025-05-30 CN claimed
CN-119019301-A Preparation method of phenolic compound 北京阳光诺和药物研究股份有限公司 2024-11-26 CN claimed
CN-116444969-B Heat-resistant flame-retardant unsaturated polyester resin and preparation method thereof 黄山明杰新材料有限公司 2024-08-27 CN claimed
CN-116444969-A Heat-resistant flame-retardant unsaturated polyester resin and preparation method thereof 黄山明杰新材料有限公司 2023-07-18 CN claimed
CN-113200894-A Synthetic method of dithio-dibutylphenol and analogue 北京中美红格科技有限公司 2021-08-03 CN claimed
CN-108425104-B Preparation method of coating taking mercapto compound as transition layer 江苏菲沃泰纳米科技有限公司 2020-02-18 CN claimed
CN-108425104-A A kind of coating production using sulfhydryl compound as transition zone 江苏菲沃泰纳米科技有限公司 2018-08-21 CN claimed
CN-103145595-B Synthesis method of probucol QILU ANTIBIOTICS LINYI PHARMACEUTICAL CO LTD 2014-03-19 CN claimed
CN-103145595-A Synthesis method of probucol QILU ANTIBIOTICS LINYI PHARMACEUTICAL CO LTD 2013-06-12 CN claimed
CN-101423484-A A kind of preparation method of probucol raw material medicine UNIV SICHUAN (CN) 2009-05-06 CN claimed
EP-0136250-B1 A PROCESS FOR PREPARATION OF MODIFIED POLYMERS THE GOODYEAR TIRE & RUBBER COMPANY (US) 1989-01-18 EP claimed
US-4772363-A Process for preparing 2,6-di-tertiarybutyl-4-mercaptophenol by electrocatalysis MERRELL DOW PHARMACEUTICALS INC. (US) 1988-09-20 US claimed
EP-0277491-A1 Process for preparing 4,4'-isopropylidenedithio-bis(2,6-di-tertiary butylphenol) by electrocatalysis MERRELL DOW PHARMACEUTICALS INC. (US) 1988-08-10 EP claimed
EP-0275952-A1 Process for preparing 2,6-ditertiarybutyl-4-mercaptophenol and 4,4'-isopropylidenedithiobis-(2,6-di-tertiarybutylphenol) MERRELL DOW PHARMACEUTICALS INC. (US) 1988-07-27 EP claimed
EP-0264129-A1 Process for preparing 2,6-ditertiarybutyl-4-mercaptophenol MERRELL DOW PHARMACEUTICALS INC. (US) 1988-04-20 EP claimed
US-4734527-A ZINC AND LEAD CATALYST MERRELL DOW PHARMACEUTICALS INC. (US) 1988-03-29 US claimed
EP-0155221-A2 A process for the preparation of functionalized monomers THE GOODYEAR TIRE & RUBBER COMPANY (US) 1985-09-18 EP claimed
EP-0140297-A2 Thiocarbamic-acid esters as stabilizers CIBA-GEIGY AG (CH) 1985-05-08 EP claimed
EP-0136250-A2 A process for preparation of modified polymers THE GOODYEAR TIRE & RUBBER COMPANY (US) 1985-04-03 EP claimed
US-4481337-A BONDING OXIDATION ANTIDEGRADANT THE GOODYEAR TIRE & RUBBER COMPANY (US) 1984-11-06 US claimed