SCHEMBL17309883

SCHEMBL17309883

CC(C)(C)c1cc(S)cc(S)c1O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 4/20 0.50
CA1 P00915 2/20 0.50
SMN1; SMN2 Q16637 5/20 0.48
ALDH1A1 P00352 5/20 0.48
POLB P06746 1/20 0.48
TYR P14679 1/20 0.48
CYP1A2 P05177 3/20 0.43
ALOX15 P16050 3/20 0.43
CYP2C9 P11712 3/20 0.43
CYP2C19 P33261 3/20 0.43
MAPT P10636 2/20 0.43
HPN P05981 1/20 0.43
SIRT5 Q9NXA8 1/20 0.43
KDM4E B2RXH2 1/20 0.42
ATP2A2 P16615 1/20 0.42
ATP2A3 Q93084 1/20 0.42
GLRA3 O75311 1/20 0.42
GLRB P48167 1/20 0.42
GAA P10253 3/20 0.39
HTT P42858 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL224048 0.88 CA2 (0.64) CA2CA1SMN1; SMN2ALDH1A1POLB
SCHEMBL6056034 0.80 SMN1; SMN2 (0.71) CA2CA1SMN1; SMN2ALDH1A1POLB
SCHEMBL1685565 0.80 CA2 (0.48) CA2CA1SMN1; SMN2ALDH1A1POLB
SCHEMBL31196962 0.80 CYP2C9 (0.63) CA2CA1SMN1; SMN2ALDH1A1POLB
SCHEMBL891539 0.80 CYP2C9 (0.63) CA2CA1SMN1; SMN2ALDH1A1POLB
SCHEMBL31196955 0.75 HSPA5 (0.53) CA2CA1SMN1; SMN2ALDH1A1POLB
SCHEMBL31196986 0.75 CA2 (0.43) CA2CA1SMN1; SMN2ALDH1A1POLB
SCHEMBL3801540 0.74
SCHEMBL21241382 0.74 CA2 (0.42) CA2CA1SMN1; SMN2ALDH1A1POLB
SCHEMBL10506187 0.74 CA2 (0.47) CA2CA1SMN1; SMN2ALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106256889-B Diesel engine oil composition and its manufacturing method 中国石油化工股份有限公司 2019-07-23 CN disclosed
CN-106318530-B Lubricant composition for gasoline engine and its manufacturing method 中国石油化工股份有限公司 2019-07-19 CN disclosed
CN-106318529-B Universal gear lubricating oil composition and its manufacturing method 中国石油化工股份有限公司 2019-06-14 CN disclosed
CN-106318527-B Methanol-fueled engine lubricant oil composite and its manufacturing method 中国石油化工股份有限公司 2019-05-17 CN disclosed
CN-105315183-B A kind of shielding phenolic compounds, its manufacturing method and its application as antioxidant 中国石油化工股份有限公司 2019-02-01 CN disclosed
CN-105218420-B A kind of shielding phenolic compounds, its manufacturing method and its application as antioxidant 中国石油化工股份有限公司 2019-02-01 CN disclosed
CN-105566720-B A kind of polymer composition and its application 中国石油化工股份有限公司 2018-11-30 CN disclosed
EP-2952505-B1 A HINDERED PHENOL COMPOUND, PREPARATION THEREOF AND USE THEREOF AS AN ANTIOXIDANT CHINA PETROLEUM & CHEM CORP (CN) 2018-05-23 EP disclosed
US-9512380-B2 Hindered phenol compound, preparation thereof and use thereof as an antioxidant CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2016-12-06 US disclosed
US-20150353858-A1 HINDERED PHENOL COMPOUND, PREPARATION THEREOF AND USE THEREOF AS AN ANTIOXIDANT RESEARCH INSTITUTE OF PETROLEUM PROCESSING, SINOPEC (CN) 2015-12-10 US disclosed
EP-2952505-A1 A hindered phenol compound, preparation thereof and use thereof as an antioxidant China Petroleum & Chemical Corporation (CN) 2015-12-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150353858-A1 HINDERED PHENOL COMPOUND, PREPARATION THEREOF AND USE THEREOF AS AN ANTIOXIDANT GPX4, CAT, GPX1 CA2 4690/4885CA1 3697/4885SMN1; SMN2 2214/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.