SCHEMBL224075

SCHEMBL224075

C=CC(=O)N1CCCCCC1=O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.46
MAPT P10636 3/20 0.43
ALDH1A1 P00352 3/20 0.43
TP53 P04637 2/20 0.43
HSD17B10 Q99714 2/20 0.43
STAT6 P42226 1/20 0.43
MITF O75030 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
KMT2A Q03164 2/20 0.35
KDM4E B2RXH2 3/20 0.35
BLM P54132 2/20 0.35
MEN1 O00255 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2D6 P10635 1/20 0.35
THRB P10828 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
RECQL P46063 1/20 0.35
GAA P10253 1/20 0.33
POLB P06746 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL225114 1.00 LMNA (0.46) LMNAMAPTALDH1A1TP53HSD17B10
SCHEMBL4362204 0.98 LMNA (0.47) LMNAMAPTALDH1A1TP53HSD17B10
SCHEMBL346131 0.92 LMNA (0.53) LMNAMAPTALDH1A1TP53HSD17B10
SCHEMBL5667561 0.90 LMNA (0.52) LMNAMAPTALDH1A1TP53HSD17B10
SCHEMBL12764295 0.84
SCHEMBL2440165 0.81 LMNA (0.41) LMNAMAPTALDH1A1TP53HSD17B10
SCHEMBL28119988 0.78 ALDH1A1 (0.51) LMNAMAPTALDH1A1TP53HSD17B10
SCHEMBL131845 0.77 LMNA (0.54) LMNAMAPTALDH1A1TP53HSD17B10
SCHEMBL8379227 0.77 LMNA (0.54) LMNAMAPTALDH1A1TP53HSD17B10
SCHEMBL5181091 0.77 LMNA (0.54) LMNAMAPTALDH1A1TP53HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 177 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2753650-B1 POLYMERIC AGENTS THAT IMPROVE PRIMARY WASHING EFFICIENCY HENKEL AG & CO KGAA (DE) 2020-04-08 EP claimed
US-20190023972-A1 SHALE SWELLING INHIBITORS ISP INVESTMENTS LLC (US) 2019-01-24 US claimed
EP-2414456-B1 DEGRADABLE POLYMER COMPOSITIONS AND USES THEREOF ISP INVESTMENTS LLC (US) 2018-12-26 EP claimed
US-10081757-B2 Shale swelling inhibitors ISP INVESTMENTS LLC (US) 2018-09-25 US claimed
EP-2346909-B1 POLYMERS DERIVED FROM N-VINYL FORMAMIDE, VINYL AMIDES OR ACRYLAMIDES, AND REACTION SOLVENT, AND THE USES THEREOF ISP INVESTMENTS INC (US) 2018-05-16 EP claimed
US-20150344767-A1 SHALE SWELLING INHIBITORS ISP INVESTMENTS INC. (US) 2015-12-03 US claimed
US-8895478-B2 Degradable polymer compositions and uses thereof ISP INVESTMENTS INC. (US) 2014-11-25 US claimed
US-20140187461-A1 POLYMERIC AGENTS THAT IMPROVE PRIMARY WASHING EFFICIENCY FRAUNHOFER-GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (DE) 2014-07-03 US claimed
WO-2014088850-A2 SHALE SWELLING INHIBITORS ISP INVESTMENTS INC. (US) 2014-06-12 WO claimed
WO-2013034437-A1 POLYMERIC AGENTS THAT IMPROVE PRIMARY WASHING EFFICIENCY HENKEL AG & CO. KGAA (DE) 2013-03-14 WO claimed
US-20120157352-A1 DEGRADABLE POLYMER COMPOSITIONS AND USES THEREOF ISP INVESTMENTS INC. (US) 2012-06-21 US claimed
US-20110277844-A1 POLYMERS DERIVED FROM N-VINYL FORMAMIDE, VINYL AMIDES OR ACRYLAMIDES, AND REACTION SOLVENT, AND THE USES THEREOF HERCULES LLC 2011-11-17 US claimed
CN-110462797-B Polishing composition 福吉米株式会社 2023-09-22 CN disclosed
EP-3939983-A1 POLYMERIZATION INITIATORS FOR FIBER-REINFORCED POLYMER COMPOSITES AND MATERIALS MADE FROM THE COMPOSITES Johns Manville (US) 2022-01-19 EP disclosed
EP-2607061-B1 Methods of making prepregs JOHNS MANVILLE (US) 2021-05-12 EP disclosed
EP-3296345-B1 HYDROLYTICALLY STABLE POLYAMIDE BLEND EVONIK OPERATIONS GMBH (DE) 2021-02-24 EP disclosed
EP-0365234-B1 Process for producing ethylenic graft copolymers SUMITOMO CHEMICAL CO (JP) 1994-05-18 EP disclosed
EP-0222129-B1 MIXTURES FROM POLYPHENYLENE ETHER AND POLYAMIDE, AND THEIR USE IN THE MANUFACTURE OF THERMOPLASTIC MOULDING COMPOSITIONS BASF Aktiengesellschaft (DE) 1990-04-04 EP disclosed
EP-0222129-A1 Mixtures from polyphenylene ether and polyamide, and their use in the manufacture of thermoplastic moulding compositions BASF Aktiengesellschaft (DE) 1987-05-20 EP disclosed
US-4590242-A Production of low-shrinkage nylon moldings BASF AKTIENGESELLSCHAFT (DE) 1986-05-20 US disclosed