Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 20/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22410614 | 0.80 | P2RX7 (0.52) | P2RX7 | |
| SCHEMBL22410771 | 0.79 | P2RX7 (0.40) | P2RX7 | |
| SCHEMBL22410657 | 0.76 | PRLHR (0.43) | P2RX7 | |
| SCHEMBL22410618 | 0.74 | SPR (0.45) | — | |
| SCHEMBL22410699 | 0.74 | HPGD (0.49) | — | |
| SCHEMBL22410888 | 0.74 | PARP1 (0.40) | P2RX7 | |
| SCHEMBL22410887 | 0.74 | P2RX7 (0.36) | P2RX7 | |
| SCHEMBL22410911 | 0.74 | MTHFD2 (0.37) | P2RX7 | |
| SCHEMBL22410634 | 0.73 | HSP90AA1 (0.37) | — | |
| SCHEMBL13249882 | 0.72 | P2RX7 (0.52) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3938362-A1 | FUSED RING PYRIMIDONE DERIVATIVES FOR USE IN THE TREATMENT OF HBV INFECTION OR OF HBV-INDUCED DISEASES | Janssen Sciences Ireland Unlimited Company (IE) | 2022-01-19 | — | — | EP | claimed |
| WO-2020182990-A1 | FUSED RING PYRIMIDONE DERIVATIVES FOR USE IN THE TREATMENT OF HBV INFECTION OR OF HBV-INDUCED DISEASES | Janssen Sciences Ireland Unlimited Company (IE) | 2020-09-17 | — | — | WO | claimed |