Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ERN1 | O75460 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | EPAS1 | Q99814 | 3/20 | 0.34 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29937848 | 1.00 | HSD17B10 (0.42) | HSD17B10ERN1ALDH1A1EPAS1AHR | |
| SCHEMBL18002847 | 0.87 | AHR (0.42) | HSD17B10ERN1AHR | |
| SCHEMBL96269 | 0.82 | ERN1 (0.41) | ERN1ALDH1A1 | |
| SCHEMBL6854243 | 0.82 | ERN1 (0.41) | ERN1ALDH1A1 | |
| SCHEMBL3477069 | 0.82 | HSD17B10 (0.52) | HSD17B10ERN1ALDH1A1AHRTDP1 | |
| SCHEMBL42392 | 0.82 | HSD17B10 (0.52) | HSD17B10ERN1ALDH1A1AHRTDP1 | |
| Hydrochloric Acid SCHEMBL28632193 | 0.79 | HSD17B10 (0.50) | HSD17B10ERN1ALDH1A1AHRTDP1 | |
| Ammonia Solution, Strong SCHEMBL13735346 | 0.79 | ERN1 (0.39) | ERN1ALDH1A1 | |
| SCHEMBL21631073 | 0.79 | ALDH1A1 (0.39) | ALDH1A1AHR | |
| SCHEMBL27286024 | 0.77 | TSHR (0.44) | ERN1EPAS1AHRPGRRAPGEF4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 224 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118496215-A | Polyhydroxylated onium derivative with disubstituted benzene ring, preparation method and medical application thereof | 中国药科大学 | 2024-08-16 | — | — | CN | claimed |
| CN-117624148-A | Polyhydroxy sulfonium salt derivative with disubstituted benzene ring, preparation method and medical application thereof | 中国药科大学 | 2024-03-01 | — | — | CN | claimed |
| US-RE48335-E1 | Polymyxin derivatives as antimicrobial compounds | MONASH UNIVERSITY (AU) | 2020-12-01 | — | — | US | claimed |
| CN-106414480-B | Polymyxin derivatives as antimicrobial compounds | 莫纳什大学 | 2020-08-04 | — | — | CN | claimed |
| US-20170137469-A1 | POLYMYXIN DERIVATIVES AS ANTIMICROBIAL COMPOUNDS | MONASH UNIVERSITY (AU) | 2017-05-18 | — | — | US | claimed |
| EP-3126376-A1 | POLYMYXIN DERIVATIVES AS ANTIMICROBIAL COMPOUNDS | Monash University (AU) | 2017-02-08 | — | — | EP | claimed |
| WO-2015149131-A1 | POLYMYXIN DERIVATIVES AS ANTIMICROBIAL COMPOUNDS | MONASH UNIVERSITY (AU) | 2015-10-08 | — | — | WO | claimed |
| US-20260042758-A1 | AZAINDOLE DERIVATIVES AND THEIR USE AS ERK KINASE INHIBITORS | AGV DISCOVERY (FR) | 2026-02-12 | — | — | US | disclosed |
| US-12545685-B2 | Dispiropyrrolidine derivatives | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2026-02-10 | — | — | US | disclosed |
| EP-4430037-B1 | ISOXAZOLIDINES AS RIPK1 INHIBITORS AND USE THEREOF | GENZYME CORP (US) | 2025-10-29 | — | — | EP | disclosed |
| EP-4626891-A1 | FUSED PYRIMIDINES AS MASP-2 INHIBITORS | Omeros Corporation (US) | 2025-10-08 | — | — | EP | disclosed |
| EP-4447962-B1 | ADENOSINE 2A RECEPTOR MODULATORS FOR USE IN THE TREATMENT OF CANCER | UNIV GENEVE (CH) | 2025-08-20 | — | — | EP | disclosed |
| WO-2025104443-A1 | INHIBITORY COMPOUNDS | STORM THERAPEUTICS LTD (GB) | 2025-05-22 | — | — | WO | disclosed |
| WO-2006034093-A2 | 3- (2-ACYLAMINO-1-HYDROXYETHYL)- MORPHOLINE DERIVATIVES AND THEIR USE AS BACE INHIBITORS | ELLI LILLY AND COMPANY (US) | 2006-03-30 | — | — | WO | disclosed |
| CN-1649865-A | Heteropolycyclic compounds and their use as metabotropic glutamate receptor antagonists | NPS PHARMA INC (US) | 2005-08-03 | — | — | CN | disclosed |
| EP-0318704-B1 | 3-CYANO-4-PHENYL-PYRROLE DERIVATIVES | BAYER AG (DE) | 1992-12-02 | — | — | EP | disclosed |
| EP-0339417-B1 | 3-CYANO-4-PHENYL-PYRROLES | BAYER AG (DE) | 1991-09-11 | — | — | EP | disclosed |
| US-5015757-A | Fungicides | BAYER AKTIENGESELLSCHAFT (DE) | 1991-05-14 | — | — | US | disclosed |
| US-4960789-A | FUNGICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1990-10-02 | — | — | US | disclosed |
| EP-0318704-A2 | 3-Cyano-4-phenyl-pyrrole derivatives | BAYER AG (DE) | 1989-06-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12545685-B2 | Dispiropyrrolidine derivatives | TP53, MDM2, TP53BP1 | HSD17B10 2895/4885ERN1 1336/4885ALDH1A1 2383/4885 |
| US-20260042758-A1 | AZAINDOLE DERIVATIVES AND THEIR USE AS ERK KINASE INHIBITORS | BRAF, RAF1, NRAS | HSD17B10 3563/4885ERN1 489/4885ALDH1A1 1307/4885 |
| US-20170137469-A1 | POLYMYXIN DERIVATIVES AS ANTIMICROBIAL COMPOUNDS | VIP, PEPD, NRDC | HSD17B10 4287/4885ERN1 1340/4885ALDH1A1 4861/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.