SCHEMBL3477069

SCHEMBL3477069

O=Cc1cc(Cl)cc(C=O)c1

nearest known ligand 0.52

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.52
ERN1 O75460 4/20 0.46
ALDH1A1 P00352 2/20 0.46
TSHR P16473 1/20 0.41
AHR P35869 1/20 0.40
TDP1 Q9NUW8 1/20 0.39
CYP2A6 P11509 1/20 0.36
VCAM1 P19320 1/20 0.35
PTPN1 P18031 1/20 0.35
TYR P14679 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL42392 0.94 HSD17B10 (0.52) HSD17B10ERN1ALDH1A1TSHRAHR
Hydrochloric Acid SCHEMBL28632193 0.91 HSD17B10 (0.50) HSD17B10ERN1ALDH1A1TSHRAHR
SCHEMBL18002619 0.87 HSD17B10 (0.42) HSD17B10ERN1ALDH1A1TSHRAHR
SCHEMBL31736848 0.87 HSD17B10 (0.42) HSD17B10ERN1ALDH1A1TSHRAHR
SCHEMBL308093 0.83 ALDH1A1 (0.47) HSD17B10ALDH1A1TSHRCYP2A6TYR
SCHEMBL12527375 0.82 HSD17B10 (0.42) HSD17B10ERN1ALDH1A1TSHRAHR
SCHEMBL237896 0.82 ALDH1A1 (0.46) HSD17B10ERN1ALDH1A1TSHRAHR
SCHEMBL2549975 0.82 ERN1 (0.48) HSD17B10ERN1ALDH1A1TSHR
SCHEMBL2011005 0.82 CYP2A6 (0.42) HSD17B10ERN1ALDH1A1AHRCYP2A6
SCHEMBL15618821 0.82 CYP3A4 (0.55) HSD17B10ERN1ALDH1A1TSHRAHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118047719-B Be used for Abeta1-42Preparation and application of quinolinium photosensitizer for protein imaging and viscosity imaging 华南理工大学 2024-06-28 CN claimed
CN-118047719-A Be used for Abeta1-42Preparation and application of quinolinium photosensitizer for protein imaging and viscosity imaging 华南理工大学 2024-05-17 CN claimed
CN-118047719-B Be used for Abeta1-42Preparation and application of quinolinium photosensitizer for protein imaging and viscosity imaging 华南理工大学 2024-06-28 CN disclosed
US-20240166867-A1 THERMOPLASTIC RESIN AND OPTICAL LENS INCLUDING SAME MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2024-05-23 US disclosed
CN-118047719-A Be used for Abeta1-42Preparation and application of quinolinium photosensitizer for protein imaging and viscosity imaging 华南理工大学 2024-05-17 CN disclosed
EP-4286448-A1 THERMOPLASTIC RESIN AND OPTICAL LENS INCLUDING SAME MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2023-12-06 EP disclosed
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed
WO-2022163674-A1 THERMOPLASTIC RESIN AND OPTICAL LENS INCLUDING SAME 三菱瓦斯化学株式会社 2022-08-04 WO disclosed
WO-2022163684-A1 CYCLIC DIOL COMPOUND, METHOD FOR PRODUCING SAID COMPOUND, AND USE OF SAID COMPOUND 新日本理化株式会社 2022-08-04 WO disclosed
US-20110313158-A1 Two Component Recyclable Heterogeneous Catalyst, Process for Preparation Thereof and its Use for Preparation of Amines COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2011-12-22 US disclosed
WO-2010097815-A2 A TWO COMPONENT RECYCLABLE HETEROGENEOUS CATALYST, PROCESS FOR PREPARATION THEREOF AND ITS USE FOR PREPARATION OF AMINES COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2010-09-02 WO disclosed
EP-0236737-B1 PROCESS FOR MAKING ULTRATHIN POLYHETEROAROMATIC FILMS Research Development Corporation of Japan (JP) 1992-08-05 EP disclosed
EP-0188675-B1 ULTRATHIN POLYMERIC IMINE FILMS AND PROCESS FOR MAKING THE SAME Research Development Corporation of Japan (JP) 1991-06-05 EP disclosed
US-4966743-A Process for making ultrathin polymeric imine films RESEARCH DEVELOPMENT CORPORATION OF JAPAN (JP) 1990-10-30 US disclosed
EP-0384392-A1 Cyanation of haloaromatics utilizing catalysts generated in situ starting with NiCl2 or NiCl2 6H2O OCCIDENTAL CHEMICAL CORPORATION (US) 1990-08-29 EP disclosed
US-4818593-A Ultrathin heteroaromatic polymer films and process for making the same RESEARCH DEVELOPMENT CORP. OF JAPAN (JP) 1989-04-04 US disclosed
US-4778720-A PRODUCT OF DIAMINE AND DIIMINE SCHIFF BASE; SEMICONDUCTORS RESEARCH DEV. CORP. OF JAPAN (JP) 1988-10-18 US disclosed
EP-0236737-A2 Process for making ultrathin polyheteroaromatic films Research Development Corporation of Japan (JP) 1987-09-16 EP disclosed
US-4681799-A Ultrathin polymeric imine films and process for making the same RESEARCH DEVELOPMENT CORP. OF JAPAN (JP) 1987-07-21 US disclosed
EP-0188675-A1 Ultrathin polymeric imine films and process for making the same Research Development Corporation of Japan (JP) 1986-07-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110313158-A1 Two Component Recyclable Heterogeneous Catalyst, Process for Preparation Thereof and its Use for Preparation of Amines HCN2, RAC2, HCN1 HSD17B10 1800/4885ERN1 1195/4885ALDH1A1 1225/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.